The aim of the investigation was to study a possibility to prevent the effects of geomagnetic storms (GMS) on cardiovascular patients. The subjects were patients with stage II to III essential hypertension and functional class II to III coronary artery disease, who were divided into three groups. Patients in group I received basic pharmacotherapy; patients in group II were treated with basic medications plus vitamin E; patients in group III received basic medications plus melatonin (melaxen). Vitamin E and melaxen were administered during a calm period, three days before a GMS, on the day of a GMS, and during three subsequent days. Besides clinico-instrumental examination, the patients were questioned for a range of clinical data. The results of the study substantiate the use of melatonin as a measure to prevent the influence of GMS.

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