As many as 46 men suffering from coronary heart disease combined with angina pectoris of effort, functional classes II-IV, were examined. The two-week treatment with nifedipine (30-60 mg/day) and aldizem (180-270 mg/day) exerted an antianginal action in 47.8 and 39.1% of the cases, respectively, which was supported by the data of clinical examinations, loading tests, and by the data of ECG monitoring. Nifedipine turned out most effective in patients of functional class II with arterial hypertension.
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