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Real-World Efficacy and Safety of Avelumab Plus Axitinib in Metastatic Renal Cell Carcinoma: Results from the Ambispective RAVE-Renal Study.
Curr Oncol
December 2024
Saint-Petersburg State University, 199034 Saint-Petersburg, Russia.
Background: The RAVE-Renal study was conducted to evaluate the real-world efficacy and safety of avelumab plus axitinib as a first-line therapy for patients with metastatic renal cell carcinoma (mRCC).
Methods: RAVE-Renal was a multicenter, noninterventional, ambispective study with both retrospective and prospective components. The study included adult patients with histologically confirmed mRCC, measurable disease per RECIST version 1.
Specialist pharmacist prescribing in dermatology.
Future Healthc J
December 2024
Lead Dermatology Pharmacist, East Lancashire Hospitals NHS Trust, United Kingdom.
Across the country, pharmacists are developing their professional competencies to move outside the dispensary and directly integrate with specialist teams. Within dermatology, the widespread use of high-cost and high-risk pharmacological interventions presents a range of opportunities for a pharmacist to contribute to safer, more cost-effective use of medicines. As well as using prescribing qualifications to take on clinical workloads, pharmacists can enact cost-saving changes to routine prescribing; improve clinical governance and use their expertise in medicines to effectively advocate for access to new or alternative treatment options, as well as demystify complex funding pathways.
View Article and Find Full Text PDFThe association of state policies and opioid analgesic amount dispensed from retail pharmacies.
Drug Alcohol Depend
February 2025
RAND, Boston, MA, United States. Electronic address:
Importance: States have implemented multiple policies likely to influence opioid prescribing; few national general population studies examine those policies' effects on per-capita opioid morphine milligram equivalents (MME) dispensed.
Objective: To examine state policies' effects on opioids per-capita MMEs dispensed at retail pharmacies.
Design: A longitudinal study of associations between MME per capita and implementation of policy interventions at different times across states.
A case of simultaneous bilateral pulmonary resection for arteriovenous pulmonary malformation.
Indian J Thorac Cardiovasc Surg
February 2025
Sechenov First Moscow State Medical University, Moscow, Russia.
Pulmonary arteriovenous malformation (PAVM) is a congenital vascular pathology, which is caused by the presence of a direct connection between the branches of the artery and the veins of the lungs, and the discharge of unoxygenated blood into the arterial bed. Arteriovenous malformations are characterized by a wide variety of clinical manifestations and, in some cases, may be accompanied with severe circulatory disorders.
View Article and Find Full Text PDFEmerging trends in cannabis administration for women with chronic pain.
Mental Health Sci
December 2024
School of Psychology, Fielding Graduate University, Santa Barbara, California, USA.
Cannabis use among women who experience chronic pain is on the rise in the United States. However, little is known about women's motives and preferences for cannabis administration. The purpose of this study was to characterize cannabis use among women with chronic pain.
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