Objective: Carcinoma cuniculatum is a rare variant of low-grade squamous cell carcinoma. We report the second case of carcinoma cuniculatum of the larynx in the literature.
Method: Case report and review of the world literature concerning carcinoma cuniculatum of the larynx and upper aerodigestive tract.
Results: A histologically proven carcinoma cuniculatum of the larynx is reported in a 72-year-old man. The patient underwent a supracricoid laryngectomy with crico-hyoidopexy, and was free of disease at 70 months after surgery. We emphasise the clinical presentation, histology and therapeutic approach of this rare tumour.
Conclusion: To our knowledge this is the second report in the world literature of carcinoma cuniculatum of the larynx. Carcinoma cuniculatum of the larynx must be considered as a distinct 'clinicopathological entity' and close cooperation between the clinician and the pathologist is essential for the correct diagnosis of these tumour as regards to the correct classification and therapy.
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http://dx.doi.org/10.1017/S0022215107000163 | DOI Listing |
J Stomatol Oral Maxillofac Surg
November 2024
Department of Pathology, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil. Electronic address:
Arch Plast Surg
November 2024
Department of Plastic Surgery, Hospital General Universitario Dr. Balmis, Alicante, Spain.
Carcinoma cuniculatum is a variant of squamous cell carcinoma, characterized by a slow growth with progressive crypt-like invasion of deep tissue. This tumor is frequently misdiagnosed as a benign skin lesion both clinically and histopathologically. The final diagnosis is often delayed as it requires a large sample biopsy.
View Article and Find Full Text PDFAm J Dermatopathol
January 2025
Department of Dermatology, University Hospital of Limoges, Limoges, France ; and.
J Maxillofac Oral Surg
August 2024
Oral and Maxillofacial Surgery Department, University Hospital Ramon y Cajal, Madrid, Spain.
Background: Oral carcinoma cuniculatum (CC) is a rare variant of squamous cell carcinoma. It exhibits a locally aggressive behaviour, and its histopathology poses a diagnostic challenge, as it can be mistaken for other conditions. We present five cases of oral CC treated at our institution and conduct a comprehensive review of the current literature.
View Article and Find Full Text PDFTurk Patoloji Derg
July 2024
Department of Pathology, University College of Medical Sciences & Guru Teg Bahadur Hospital, DELHI, INDIA.
Carcinoma cuniculatum (CC) is a rare and distinct clinicopathological variant of well-differentiated squamous cell carcinoma. It is a rare and slow-growing tumor with a peculiar infiltrative growth pattern resembling rabbit burrows (cuniculi). It usually occurs over the plantar aspect of the foot but can also occur at other sites like the oral cavity and genitals.
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