Development of urinary continence, which is necessary for species survival and comfort of human being, begins with the organization of vesico-sphincteric automatism, as part of nervous system growth. Micturitional reflex are successively integrated inside the ganglionic plexuses in the foetus, the sacral spinal cord in the newborn and the pontine center in the child. Voluntary control of this automatism needs, at first, feeling an sensitive information about the bladder fullness, that is to say a "desire of urinate". Child first controls his striated sphincter, what makes him able to avoid urine leakage and enlarges his bladder capacity. Latter, he can initiate or refuse, voluntarily, bladder contraction, doing his bladder the most intelligent organ and, consequently, the most psychologically vulnerable one. Timing of these different steps is variable; in addition to the natural maturity processes which progress more or less quickly, training adds it effects, more useful for developing continence during daytime than during night-time.
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BMC Urol
January 2025
Department of Urology, Fukushima Medical University School of Medicine, 1, Hikarigaoka, Fukushima, 960-1295, Japan.
Background: Long-term survival can be achieved in patients with localized prostate cancer (PCa). Therefore, maintenance of postoperative quality of life (QOL) and treatment satisfaction are important. Although longitudinal changes in disease-specific QOL are reported, there are few studies investigating which factors longitudinally affect treatment satisfaction in patients who undergo robot-assisted radical prostatectomy (RARP).
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January 2025
Department of Colorectal Surgery, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, 222 Banpodearo, Seochogu, Seoul, 06591, Korea.
Metastatic lateral pelvic lymph node (LPN) in rectal cancer has a significant clinical impact on the prognosis and treatment strategies. But there are still debates regarding prediction of lateral pelvic lymph node metastasis and its oncological impact. This review explores the evidence for predicting lateral pelvic lymph node metastasis and survival in locally advanced rectal cancer.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
January 2025
Department of Cardiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Background: Adrenal Vein Sampling (AVS) is the gold standard for categorizing primary aldosteronism (PA). However, catheterization of the right adrenal vein (RAV) can be technically challenging. This study aimed to investigate the validity of the right renal vertebral contour as fluoroscopic landmarks to help RAV orifice localization during AVS.
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January 2025
Department of Urology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Background And Objective: Radiation-induced cystitis (RIC) is an important consequence of pelvic radiotherapy that can cause high morbidity and, in extreme cases, mortality. The lack of a widely accepted classification system makes it difficult to compare treatment regimens. Our aim was to develop a new classification system covering the RIC spectrum to improve treatment comparisons and accurate incidence estimates for systematic use in clinical and research settings.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Endocrinology and Metabolism, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea.
Sodium-glucose co-transporter 2 inhibitors, such as enavogliflozin, offer promising metabolic benefits for patients with type 2 diabetes (T2D), including glycemic control and improved cardiac function. Despite the clinical evidence, real-world evidence is needed to validate their safety and effectiveness. This study aims to evaluate the effects of weight loss and safety of enavogliflozin administration in patients with T2D in a real-world clinical setting over 24 weeks.
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