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Compassion in the justification of physician-assisted dying: Gandhi's non-violence vs. Aristotle's virtues and vices.
Med Health Care Philos
January 2025
Duquesne University, 600 Forbes Ave, Pittsburgh, PA, 15282, USA.
Compassion is an essential phenomenon in the therapeutic relationship, and some use it to justify physician-assisted dying practices. The value of compassion in the relationship between healthcare professionals and patients is undeniable. However, different approaches to its definition and scope can lead to distinct conclusions about the role of compassion in end-of-life interventions.
View Article and Find Full Text PDFVirtue Ethics in a Value-driven World: "Voluntourism" and Effective Altruism.
Clin Orthop Relat Res
January 2025
Chief, Penn Orthopaedics Foot and Ankle Service, The Hospitals of the University of Pennsylvania, Philadelphia, PA, USA.
Was Aristotle right about moral decision-making? Building a new empirical model of practical wisdom.
PLoS One
January 2025
Jubilee Centre for Character and Virtues, University of Birmingham, Birmingham, United Kingdom.
This article presents the development and validation of the Short Phronesis Measure (SPM), a novel tool to assess Aristotelian phronesis (practical wisdom). Across three studies, using large, nationally representative samples from the UK and US (demographically matched to census data), we employed a systematic and rigorous methodology to examine the structure, reliability, and validity of the SPM. In Study 1a, exploratory factor analysis identified ten distinct, internally reliable components of phronesis, challenging the traditional four-component Aristotelian model.
View Article and Find Full Text PDFThe virtues of limits and environmental sustainability in healthcare.
Bioethics
January 2025
Plunkett Centre for Ethics, Australian Catholic University, Darlinghurst, New South Wales, Australia.
The spectre of human-induced climate change has drawn attention to the need to discover new, environmentally sustainable approaches to healthcare. This article draws upon David McPherson's The Virtues of Limits (2021) to develop a virtue ethics for sustainability in healthcare. I explore how a virtuous appreciation of the value of healthcare resources can lead us to exercise stewardship in our use of those resources, whereas a failure to appreciate the value of resources can lead to irresponsible and unsustainable patterns of use.
View Article and Find Full Text PDFMultiplex immunohistochemistry to explore the tumor immune microenvironment in HCC patients with different GPC3 expression.
J Transl Med
January 2025
Comprehensive Cancer Center, Department of Oncology, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, 321 Zhongshan Road, Nanjing, 210008, China.
Objectives: GPC3 has been recognized as a promising target for immunotherapy in hepatocellular carcinoma (HCC). However, the GPC3-targeted immunotherapies have shown limited therapeutic efficacy. The use of anti-PD-1/PD-L1 monoclonal antibodies in HCC treatment is considerably constrained.
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