In this work, we propose a mesoscopic model for tumor growth to improve our understanding of the origin of the heterogeneity of tumor cells. In this sense, this stochastic formalism allows us to not only to reproduce but also explain the experimental results presented by Brú. A significant aspect found by the model is related to the predicted values for beta growth exponent, which capture a basic characteristic of the critical surface growth dynamics. According to the model, the value for growth exponent is between 0,25 and 0,5, which includes the value proposed by Kadar-Parisi-Zhang universality class (0,33) and the value proposed by Brú (0,375) related to the molecular beam epitaxy (MBE) universality class. This result suggests that the tumor dynamics are too complex to be associated to a particular universality class.
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http://dx.doi.org/10.3934/mbe.2007.4.687 | DOI Listing |
Int J Surg
January 2025
Carcinoma Department of Traditional Chinese Medicine, Dianjiang People's Hospital of Chongqing, Chongqing, PR China.
The widespread adoption of high-resolution computed tomography (CT) screening has led to increased detection of small pulmonary nodules, necessitating accurate localization techniques for surgical resection. This review examines the evolution, efficacy, and safety of various localization methods for small pulmonary nodules. Studies focusing on localization techniques for pulmonary nodules ≤30 mm in diameter were included, with emphasis on technical success rates and complication profiles.
View Article and Find Full Text PDFGastroenterology
February 2025
Section of Gastroenterology and Hepatology, Veterans Affairs Northeast Ohio Health Care System, Cleveland, Ohio; Division of Gastroenterology and Hepatology, Case Western Reserve University, Cleveland, Ohio.
Background & Aims: Hepatitis B reactivation (HBVr) can occur due to a variety of immune-modulating exposures, including multiple drug classes and disease states. Antiviral prophylaxis can be effective in mitigating the risk of HBVr. In select cases, clinical monitoring without antiviral prophylaxis is sufficient for managing the risk of HBVr.
View Article and Find Full Text PDFSensors (Basel)
January 2025
Department of Electrical and Computer Engineering, Illinois Institute of Technology, Chicago, IL 60616, USA.
Universal image segmentation aims to handle all segmentation tasks within a single model architecture and ideally requires only one training phase. To achieve task-conditioned joint training, a task token needs to be used in the multi-task training to condition the model for specific tasks. Existing approaches generate the task token from a text input (e.
View Article and Find Full Text PDFMaterials (Basel)
January 2025
Department of Restorative Dentistry, School of Dentistry, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre 90619-900, Brazil.
The aim of this study was to evaluate, in vitro, the void formation and marginal adaptation in Class II cavities restored with preheated and injected bulk-fill resin composites. Eighty third molars received Class II cavities on their mesial and distal surfaces and were randomly distributed into eight groups (n = 10) according to material (Filtek Universal-control, incremental technique; Filtek One Bulk-Fill; Admira Fusion X-tra Bulk-Fill; VisCalor Bulk-Fill) and the temperature of the material (24 °C or 68 °C). The restored teeth were scanned using a SkyScan 1173 microtomograph.
View Article and Find Full Text PDFInt J Mol Sci
January 2025
Department of Rare Diseases, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14, 61-704 Poznan, Poland.
Circular RNAs (circRNAs) are a class of unique transcripts characterized by a covalently closed loop structure, which differentiates them from conventional linear RNAs. The formation of circRNAs occurs co-transcriptionally and post-transcriptionally through a distinct type of splicing known as back-splicing, which involves the formation of a head-to-tail splice junction between a 5' splice donor and an upstream 3' splice acceptor. This process, along with exon skipping, intron retention, cryptic splice site utilization, and lariat-driven intron processing, results in the generation of three main types of circRNAs (exonic, intronic, and exonic-intronic) and their isoforms.
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