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A genome-wide association study identifies genetic variants associated with hip pain in the UK Biobank cohort (N = 221,127).
Sci Rep
January 2025
Nottingham Ningbo China Beacons of Excellence Research and Innovation Institute, University of Nottingham Ningbo China, Ningbo, 315100, China.
Hip pain is a common musculoskeletal complaint that leads many people to seek medical attention. We conducted a primary genome-wide association study (GWAS) on the hip pain phenotype within the UK Biobank cohort. Sex-stratified GWAS analysis approach was also performed to explore sex specific variants associated with hip pain.
View Article and Find Full Text PDFCohort profile: A prospective cohort study on newlywed couples in rural and poor urban Bangladesh.
PLoS One
January 2025
Maternal and Child Health Division, icddr,b, Dhaka, Bangladesh.
Sexual and Reproductive Health and Rights (SRHR) aim to enhance quality of life through safe sexual experiences, reproductive autonomy, and protection against gender-based violence. However, existing SRHR research and interventions in low- and middle-income countries like Bangladesh predominantly focus on women, often understating men and neglecting the nuanced contextual issues faced by married couples. This study contributes to filling this gap by examining SRHR dynamics among newlyweds in rural and poor urban areas of Bangladesh, especially focusing on marital satisfaction, fertility preferences, and post-marriage adaptation mechanisms.
View Article and Find Full Text PDFFrom Sevagram to National Health Policy: Dr. Sushila Nayar's Contributions to Rural Healthcare and Medical Education in India.
Cureus
December 2024
Community Medicine, Dr. Dnyandeo Yashwantrao Patil Medical College, Hospital and Research Centre, Dr. Dnyandeo Yashwantrao Patil Vidyapeeth (Deemed to be University), Pune, IND.
Dr. Sushila Nayar (1914-2001) was a pioneering figure in Indian public health whose work spanned from grassroots initiatives to national policy formation. This review article traces Dr.
View Article and Find Full Text PDFPrussian Blue Nanozyme Featuring Enhanced Superoxide Dismutase-like Activity for Myocardial Ischemia Reperfusion Injury Treatment.
ACS Nano
January 2025
Jiangsu Key Laboratory for Biomaterials and Devices, School of Biomedical Sciences and Medical Engineering, Southeast University, Nanjing 210096, P. R. China.
The blood flow, when restored clinically following a myocardial infarction (MI), disrupts the physiological and metabolic equilibrium of the ischemic myocardial area, resulting in secondary damage termed myocardial ischemia-reperfusion injury (MIRI). Reactive oxygen species (ROS) generation and inflammatory reactions stand as primary culprits behind MIRI. Current strategies focusing on ROS-scavenging and anti-inflammatory actions have limited remission of MIRI.
View Article and Find Full Text PDFOnline profiling of volunteers in public health emergencies: insights from COVID-19 in China.
BMC Public Health
January 2025
School of Management, Nanjing University of Posts and Telecommunications, No.66 Xin Mofan Road, Nanjing, Jiangsu, 210003, China.
Background: During public health emergencies, the diverse backgrounds of volunteers pose numerous management challenges. This study aims to develop an online profiling model of volunteers using social media data to achieve a more comprehensive and objective understanding of them.
Methods: In the proposed model, the study designed five profiling tags: basic information, sentiment, topic features, interest preferences, and online social engagement.
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