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Case report: Adult case of A20 haploinsufficiency suspected as neuro-Behçet disease.
Front Immunol
January 2025
Department of Rheumatology & Allergology, Japanese Red Cross Medical Center, Tokyo, Japan.
Patients with A20 haploinsufficiency (HA20) presenting with central nervous system (CNS) symptoms are rare, and available reports are limited. Here, we describe a patient with HA20, previously followed up as Behçet disease, who presented with CNS symptoms in adulthood. A 38-year-old Japanese male who had been followed up for incomplete Behçet disease at another hospital since 28 years of age presented to our hospital with acute-onset diplopia and persistent hiccups that were severe enough to cause vomiting.
View Article and Find Full Text PDFA Case of Bronchopneumonia Presenting With Persistent Hiccups Successfully Treated With Clonazepam and a Traditional Kampo Medicine.
Cureus
December 2024
Division of Nephrology, Toho University Sakura Medical Center, Sakura, JPN.
Persistent hiccups are rare but can serve as an early symptom of underlying conditions, including pulmonary infections and cerebrovascular disorders. This case highlights hiccups as a presenting symptom of bronchopneumonia in a hemodialysis patient and explores the effective use of chlorpromazine and Hange-koboku-to (HKT) as symptomatic therapies. Given the potential association of hiccups with neurological conditions, this case underscores the need for comprehensive diagnostic evaluation.
View Article and Find Full Text PDFUnveiling the Masked Culprit: Central Nervous System Infection With Varicella-Zoster Virus Diagnosed by Multiplex PCR in an Elderly Patient With Atypical Neurological Symptoms.
Cureus
October 2024
Department of Neurology, Toho University Ohashi Medical Center, Tokyo, JPN.
Article Synopsis
- * Using cerebrospinal fluid multiplex polymerase chain reaction (PCR) testing, doctors quickly identified VZV, leading to immediate antiviral treatment.
- * This situation emphasizes the need to think about VZV in rare neurological cases and showcases how multiplex PCR can improve diagnosis, especially in cases without common symptoms.
Cardioneuroablation eliminating cardiac asystole associated with area postrema syndrome: a case report and literature review.
Front Cardiovasc Med
October 2024
Department of Cardiovascular Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Article Synopsis
- A young patient with neuromyelitis optica spectrum disorder experienced recurrent cardiac asystole and syncope following persistent hiccups, but successfully underwent cardioneuroablation (CNA) treatment, avoiding the need for a permanent pacemaker.
- Previous cases of symptomatic bradycardia-arrhythmia related to area postrema syndrome (APS) showed a significant number required pacemaker implantation, highlighting the severity of the condition.
- The findings suggest that CNA can effectively treat bradyarrhythmia associated with APS, and healthcare professionals should consider the potential link between these symptoms and APS in their clinical assessments.*
Persistent Hiccups Following Leadless Pacemaker Implantation.
R I Med J (2013)
November 2024
Associate Professor of Medicine, Emeritus, The Warren Alpert Medical School of Brown University.
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