A retrospective study on diarrheal manifestation in newborn babies was conducted at the ward of Neonatology, Dr. Pirngadi Hospital Medan from January to December 1988. There were all 3367 babies hospitalized during the study period. One hundred and thirty five (4.0%) had diarrhea, including 106 (78.5%) babies with birth weights of greater than or equal to 2500 gram. Of 2478 babies with spontaneous delivery, 34 (1.4%) babies had diarrhea, while of 889 babies with obstetrical intervention delivery 101 (11.4%) babies had diarrhea. The difference was statistically significant (p less than 0.001). Of 135 babies with diarrhea, there were 82 (60.7%) with moderate and 31 (23.0%) with severe dehydration. The mortality rate was 47.5% in patients with accompanying diseases and 0.0% in them without. The mortality rate in babies with birth weights less than 2500 gr was 37.9% and 16.9% in babies with birthweights greater than or equal to 2500 gram (p less than 0.001). The mortality rate increased with the increase of severity of dehydration (p less than 0.03).
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Eur J Pediatr
January 2025
Global Health and Tropical Medicine, GHTM, LA-REAL, Instituto de Higiene e Medicina Tropical, IHMT, Universidade NOVA de Lisboa, Lisbon, Portugal.
Purpose: Under-five mortality is a key public health indicator, highly responsive to preventive interventions. While global efforts have made strides in reducing mortality rates in this age group, significant disparities persist, particularly in Sub-Saharan Africa. This study aimed to systematically review the factors influencing under-five mortality in Africa, focusing on sociodemographic factors and health-related determinants.
View Article and Find Full Text PDFDiarrhea is a global public health problem that is the third leading cause of death in under five years, with an estimated 1.7 billion cases in 2023 and 1.8 million deaths from diarrhea diseases every year.
View Article and Find Full Text PDFTurkiye Parazitol Derg
January 2025
Sağlık Bilimleri Üniversitesi, Dr. Behçet Uz Çocuk Hastalıkları ve Cerrahisi Eğitim Araştırma Hastanesi, Mikrobiyoloji Laboratuvarı, İzmir, Türkiye.
Objective: In the study, various complaints such as gastrointestinal complaints such as diarrhea, constipation, abdominal pain, nausea and vomiting, weight loss, night urination, itching around the anus, malnutrition, malabsorption, anemia, intelligence and developmental delay were reported to University of Health Sciences Türkiye, Dr. Behçet Uz Pediatric Diseases and Surgery Training and Researhc Hospital, Microbiology Laboratory between 2017 and 2022. It was aimed to determine the frequency and distribution of intestinal parasites in patients presenting with clinical symptoms.
View Article and Find Full Text PDFMucosal Immunol
January 2025
Weill Cornell Medicine Department of Pediatrics, Division of Infectious Disease, New York, NY, USA. Electronic address:
Dimeric IgA (dIgA) is the dominant antibody in many mucosal tissues. It is actively transported onto mucosal surfaces as secretory IgA (sIgA) which plays an integral role in protection against enteric pathogens, particularly in young children. Therapeutic strategies that deliver engineered, potently neutralizing antibodies directly into the infant intestine through breast milk could provide enhanced antimicrobial protection for neonates.
View Article and Find Full Text PDFFront Public Health
January 2025
Department of Animal Sciences, Global Food Systems Institute, and Emerging Pathogens Institute, University of Florida, Gainesville, FL, United States.
Background: is associated with environmental enteric dysfunction (EED) and malnutrition in children. infection could be a linchpin between livestock fecal exposure and health outcomes in low-resource smallholder settings.
Methods: We followed a birth cohort of 106 infants in rural smallholder households in eastern Ethiopia up to 13 months of age.
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