Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract, but they have been rarely reported in the esophagus. The authors present the case of an esophageal GIST and discuss the diagnostic course and therapeutic options, as currently reported in the literature.
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Thoracoscopic and endoscopic cooperative surgery for esophageal gastrointestinal stromal tumor: a case report.
Surg Case Rep
October 2024
Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine, 1 Hikariga-Oka, Fukushima City, Fukushima, 960-1295, Japan.
Background: Esophageal gastrointestinal stromal tumors (GISTs) are relatively rare, accounting for 2-5% of all GISTs. Typically, the treatment is surgery in nature. However, no standard procedure established for esophageal GISTs, and in many cases, subtotal esophagectomy or local resection via thoracoscopy or mediastinoscopy is performed.
View Article and Find Full Text PDFA rare simultaneous coexistence of pancreatic gastrointestinal stromal tumor and esophageal schwannoma: a case report and review of literature.
Front Oncol
September 2024
Gastric Cancer Center, Department of General Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
The concurrent presence of gastrointestinal stromal tumor and schwannoma is extremely rare, and its pathological characteristics remain unclear. This case report reported the diagnostic and treatment process of a patient with a pancreatic GIST coexisting with esophageal schwannoma, who was admitted to West China Hospital (Sichuan, China) in April 2015. The patient did not undergo surgical resection of the tumor but instead received an 8-year regimen of imatinib therapy, during which no tumor progression was observed.
View Article and Find Full Text PDFIncidence and Survival Outcomes of Gastrointestinal Stromal Tumors.
JAMA Netw Open
August 2024
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland.
Article Synopsis
- The study analyzes the rise in gastrointestinal stromal tumors (GISTs) incidence since GIST-specific coding started in 2001, using data from the National Cancer Institute's SEER Program.
- It includes patients aged 20 and older diagnosed between 2000 and 2019, focusing on trends in incidence rates based on factors like race, ethnicity, and sex.
- Findings show a significant increase in GIST incidence across most organ sites except the colon, with variations in rates observed by demographic factors.
[Diagnostic yield and utility of boring biopsy for subepithelial lesions of the stomach and esophagus].
Nihon Shokakibyo Gakkai Zasshi
August 2024
Department of Gastroenterology, National Hospital Organization Himeji Medical Center.
Article Synopsis
- The study assessed the effectiveness of boring biopsy in diagnosing subepithelial lesions (SEL) in the stomach and esophagus, involving 52 patients.
- The diagnostic yield was found to be 50% for gastric SELs and 80% for esophageal SELs, with higher success rates for smaller lesions (less than 10mm).
- Complications occurred in 10% of stomach biopsies, including two perforations and two cases of bleeding, while gastrointestinal stromal tumors were identified in 43% of gastric cases and all esophageal SELs were leiomyomas.
Optimal management options for esophageal gastrointestinal stromal tumors (E-GIST).
Eur J Surg Oncol
September 2024
Department of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China. Electronic address:
Objective: To explore the different treatment modalities for esophageal gastrointestinal stromal tumors (E-GIST) and their respective applicability and clinical outcomes.
Methods: This is a retrospective study in which consecutive patients diagnosed with E-GIST at our hospital from January 2017 to August 2023 were included. The clinical characteristics of all the patients as well as long-term quality of life were recorded and analyzed.
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