Comparison between therapeutic regimes in erosive chronic gastritis associated with Helicobacter pylori.

Minerva Gastroenterol Dietol

Divisione di Chirurgia Generale, Servizio di Endoscopia Digestiva, Regione Lombardia, USSL n. 44, Ospedale Civile di Montichiari, Brescia, Italy.

Published: December 1996

Following numerous reports confirming the role of erosive chronic gastritis and ulcer, several treatment protocols have been used with the aim of eradicating this microorganism. Elimination was initially achieved using polychemotherapeutic associationsbismuth salts+metronidazole+amoxycillin and/or tetracyclineswhich proved relatively efficacious in therapeutic terms, but often led to side effects, the onset of bacterial resistance and scarse patient compliance. The authors consider that these limits can be overcome by using a new association of homeprazole+azithromycin, whose effica-cy in the eradication of Helicobacter pylo-ri has been shown to be of about 85% of cases treated for a relatively short period (4 weeks).

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