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Post-operative oropharyngeal rehabilitation suppress oxidative stress and inflammation in obstructive sleep apnea patients with transoral robotic surgery.
J Formos Med Assoc
March 2025
Department of Otolaryngology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Department of Environmental and Occupational Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Electronic address:
Purpose: To demonstrate the effects of postoperative oropharyngeal rehabilitation on inflammatory mediators and antioxidant capacity in adults with obstructive sleep apnea.
Methods: This quasi-experimental study enrolled participants without blinding between January 2020 and December 2022. Patients with obstructive sleep apnea were divided into a conservative treatment group (n = 17), surgery group (n = 23), or surgery combined with oropharyngeal rehabilitation (surgery + rehabilitation) group (n = 19).
Comparing outcomes of endovascular intervention vs bypass surgery for patients with chronic/critical limb ischemia.
Cardiovasc Revasc Med
March 2025
FSCAI - Cleveland Clinic Main Campus, Cleveland, OH, United States of America.
Background: Chronic Limb Threat Ischemia (CLTI) is a severe form of peripheral arterial disease characterized by various symptoms including nonhealing wounds, ulcers and gangrene ultimately leading to a possible amputation. Therefore, revascularization either through endovascular intervention (EVI) or surgical bypass (SB) is an important step in management. Literature review of various studies including Randomized clinical trials (RCTs), Meta-analysis and observational studies show varied results with some studies suggesting better outcomes with EVI while majority of the others favors superiority of SB.
View Article and Find Full Text PDFTransfusion of modified whole blood versus blood components therapy in patients with severe trauma: Randomized controlled trial protocol (WEBSTER trial).
Injury
January 2025
División de Cirugía de Trauma y Emergencias, Departamento de Cirugía, Fundación Valle del Lili, Cali, Colombia; Departamento de Cuidado Intensivo, Fundación Valle del Lili, Cali, Colombia; Departamento de Cirugía, Universidad del Valle, Cali, Colombia.
Hemostatic resuscitation is a mainstay in the management of trauma patients. Factors such as blood loss and tissue injury contribute to coagulation and hemodynamic status imbalances. Hemorrhage remains a leading cause of death in trauma patients, despite advances in strategies such as damage control surgery, massive transfusion protocol, and intensive care.
View Article and Find Full Text PDFImaging in sarcoid disease.
Best Pract Res Clin Rheumatol
March 2025
Department of Radiology, Mayo Clinic, 200 1st St SW, Rochester, MN, 55902, USA. Electronic address:
Sarcoidosis is a complex multisystem inflammatory disease characterized by noncaseating granulomas and variable clinical manifestations, most commonly affecting the lungs, skin, heart, and nervous system. Imaging is central in its diagnosis, staging, and management, providing essential insights into organ involvement and disease activity. Pulmonary manifestations remain the hallmark, with modalities such as high-resolution chest computed tomography (CT) and chest radiography offering critical diagnostic clues.
View Article and Find Full Text PDFHand function recovery after extended radial forearm free flap: A case series of a progressive therapy protocol.
J Hand Ther
March 2025
Department of Plastic Surgery, Vanderbilt University Medical Center, Nashville 37232, TN, USA. Electronic address:
Background: Restoration of hand function postextended radial forearm free flap (E-RFFF) is vital but challenging due to complex forearm anatomy and potential complications like reduced range of motion and sensory deficits. Traditional rehabilitation protocols often do not effectively address these issues.
Purpose: This study aims to explore the effectiveness of a hand therapy protocol that incorporates early active motion to enhance recovery outcomes after E-RFFF.
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