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Adv Emerg Nurs J
December 2024
Author Affiliations: Sharp Chula Vista Medical Center, Sharp Healthcare, Chula Vista, California (Mss Gomez and LeClair, Drs Jenkins and David, and Ms Downing); and School of Nursing, San Diego State University, San Diego, California (Dr Graham).
Background: Delays in sepsis recognition contribute to delays in antibiotic administration, which lead to increased morbidity and mortality in patients with sepsis. Our objective was to create an Emergency Department (ED) Code Sepsis Nurse-led team to reduce the time to antibiotics and mortality in patients with sepsis.
Methods: This initiative was implemented at a community hospital in Southern California in response to previous undesirable sepsis outcomes.
BMJ Open Qual
July 2021
Department of Emergency Medicine, All India Institute of Medical Sciences, New Delhi, India.
Introduction: Failure of early identification of sepsis in the emergency department (ED) leads to significant delays in antibiotic administration which adversely affects patient outcomes.
Aim: The primary objective of our Quality Improvement (QI) project was to reduce the door-to-antibiotic time (DTAT) by 30% from the preintervention in patients with suspected sepsis. Secondary objectives were to increase the blood culture collection rate by 30% from preintervention, investigate the predictors of improving DTAT and study the effect of these interventions on 24-hour in-hospital mortality.
Am J Emerg Med
February 2018
Lakeland Regional Health Medical Center, Department of Pharmacy, 1324 Lakeland Hills Blvd, Lakeland, FL 33805, United States. Electronic address:
Background: Targeted antibiotic treatment reduces the infection risk of open fractures when soft tissue and bone are exposed to the environment. The risk of infection increases with higher degrees of injury. The Gustilo-Anderson system was developed to identify the degree of injury of open fractures and can be utilized to guide initial antibiotic therapy.
View Article and Find Full Text PDFJ Emerg Med
April 2012
Department of Emergency Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Background: The Surviving Sepsis Campaign (SSC) guidelines recommend that broad-spectrum antibiotics be administered to severely septic patients within 3 h of emergency department (ED) admission. Despite the well-established evidence regarding the benefit of timely antibiotics, adoption of the SSC recommendation into daily clinical practice has been slow and sporadic.
Study Objective: To study the impact of storing broad-spectrum antibiotics in an ED automated dispensing cabinet (ADC) on the timeliness of antibiotic administration in severely septic patients presenting to the ED.
Pediatr Int
December 2011
Department of Pediatrics, Research Center, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Background: Patients with febrile neutropenia (FN) may develop severe infection, septic shock, and death. To improve the outcome of pediatric oncology patients with suspected FN, clinical practice guidelines were developed for these patients at the emergency room (ER). The objective of the present study was to evaluate compliance of the clinical practice guidelines for children with cancer presenting with fever to the ER and adverse outcomes after using the guidelines.
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