The soluble copper silicate (CS) MIC of 100 strains of methicillin-resistant Staphylococcus aureus and 100 strains of methicillin-susceptible S. aureus (MSSA) was 175 mg Cu/liter. Bactericidal and postantibiotic effects (> or =1 h) were seen at 2x MIC and 4x MIC. The frequency of mutation was <10(-9), and serial passage could not extend growth beyond 1.6x MIC.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2168014 | PMC |
| http://dx.doi.org/10.1128/AAC.00771-07 | DOI Listing |
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