AI Article Synopsis
- The study investigates how exposure to polychlorinated diphenyls (PCBs) affects the liver's cytochrome P-450 system during the perinatal period in rats.
- Researchers observed significant changes in the development of this enzyme system, which is crucial for drug metabolism and detoxification.
- The findings imply that exposure to PCBs during this critical developmental stage may disrupt normal liver function and enzyme production.
Article Abstract
Perinatal action of polychlorinated diphenyls on rat liver monooxygenase system in ontogenesis was studied. Significant modifications in the development of cytochrome P-450 system were noted.
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