Background: Stroke of unknown origin is a diagnostic and therapeutic challenge. A subgroup-analysis was performed to evaluate microembolus detection in these cryptogenic strokes.
Methods And Results: In this study, 78 patients with acute cerebral ischemia in the anterior circulation were monitored for microembolic signals (MES) by the use of transcranial doppler at admittance and 2 times at 24-hour intervals. All patients underwent routine stroke work-up. Twenty patients presented with cryptogenic ischemia. Of these 20 patients, 30% (6/20) showed MES during examination 1, 20% (4/20) in examination 2, and 20% (4/20) in examination 3.
Conclusion: MES could be detected in 45% of patients with cryptogenic ischemia. Thus, the underlying pathology may be in part embolic. The detection of MES in cryptogenic ischemia should therefore be an argument for extensive retesting to maybe identify a potential embolic source.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1053/jscd.2001.24659 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Clinical Insights on My Acute Ischemic Stroke Caused by a Carotid Web.
Cureus
December 2024
Department of Pediatrics, Japanese Red Cross Wakayama Medical Center, Wakayama, JPN.
Acute ischemic stroke, a medical emergency caused by reduced cerebral blood flow, results in brain cell damage. While commonly associated with older individuals, strokes can also occur in young and middle-aged adults, posing significant socio-economic and health challenges due to the long-term impact of the condition. This poses significant socio-economic and health challenges because stroke is a leading cause of disability and mortality.
View Article and Find Full Text PDFDifferent expression patterns of inflammation-related genes and serum microRNAs in young-onset ischemic stroke.
Sci Rep
October 2024
Department of Neurology and Neurosurgery, University of Tartu, L. Puusepa 8, 50406, Tartu, Estonia.
Article Synopsis
- * Researchers collected blood samples from 73 patients and analyzed the expression of specific genes and miRNAs using real-time quantitative PCR, revealing significant differences in gene expression patterns between the two types of stroke.
- * Findings showed that certain inflammatory genes were more upregulated during the acute phase of cryptogenic stroke compared to LAA stroke, suggesting differing inflammatory responses associated with these two stroke types.
Brain lesion and echocardiogenic predictors of newly detected atrial fibrillation in acute ischemic stroke.
Clin Neurol Neurosurg
November 2024
Department of Neurology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Republic of Korea. Electronic address:
Article Synopsis
- * Researchers analyzed data from 850 AIS patients to compare characteristics among those with AF detected after the stroke, those with known AF, and those with cryptogenic stroke (CS).
- * Findings indicated that patients with AF detected after stroke (AFDAS) generally had more severe initial strokes and greater right insular cortex lesions, but lower rates of coronary heart disease compared to those with known AF.
The primary cause of markedly elevated aminotransferases in hospitalized patients with cirrhosis in ischemic hepatitis.
Eur J Gastroenterol Hepatol
November 2024
Digestive Disease Research Center, Medical University of South Carolina, Charleston, South Carolina, USA.
Article Synopsis
- - The study investigates the reasons behind significant elevations in liver enzymes (≥1000 IU/l) in patients with cirrhosis and explores their outcomes, focusing particularly on a cohort of 152 hospitalized patients from 2012 to 2022.
- - Findings reveal that ischemic hepatitis is the most common cause of these enzyme elevations, accounting for 71% of cases, while other less frequent causes include chemoembolization, autoimmune hepatitis, and drug-induced liver injury.
- - The mortality rate during hospitalization is notably high for patients with ischemic hepatitis at 73%, contrasting sharply with a 20% mortality rate for those with other liver injury causes.
Acute Lower Limb Ischaemia as a Presenting Sign of Atrial Myxoma: Case Report and Scoping Review of the Literature.
EJVES Vasc Forum
July 2024
Department of Cardio Thoracic and Vascular Diseases, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.
Article Synopsis
- Cardiac myxomas (CMs) are rare heart tumors that can cause serious complications like acute lower limb ischaemia (ALI), particularly in younger patients.
- A study reviewed data from 59 cases of ALI caused by CM embolisation; it reported a 12.1% in-hospital mortality rate and various complication rates, but no deaths or significant issues during follow-up after discharge.
- The case of a 26-year-old woman who underwent successful surgery for ALI due to CM highlights the importance of considering CM as a potential cause when healthy young patients present with unexplained ALI symptoms.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!