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Precise diagnosis of breast phyllodes tumors using Raman spectroscopy: Biochemical fingerprint, tumor metabolism and possible mechanism.
Anal Chim Acta
December 2023
Department of Breast Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, PR China. Electronic address:
Background: Breast fibroadenomas and phyllodes tumors are both fibroepithelial tumors with comparable histological characteristics. However, rapid and precise differential diagnosis is a tough point in clinical pathology. Given the tendency of phyllodes tumors to recur, the difficulty in differential diagnosis with fibroadenomas leads to the difficulty in optimal management for these patients.
View Article and Find Full Text PDFAnal excision of perianal fibroadenoma: Expect the unexpected.
SAGE Open Med Case Rep
July 2021
Department of Surgical Sciences, 'Sapienza' University of Rome, Rome, Italy.
Breast fibroadenomas are a common benign tumour in women that may need to be surgically excised. A mammary-like fibroadenoma can exceptionally be found in the pathological report after an anal polyp removal. A 60-year-old woman presented with huge anal polyp of 25 mm.
View Article and Find Full Text PDFIntegrated local binary pattern texture features for classification of breast tissue imaged by optical coherence microscopy.
Med Image Anal
May 2017
Department of Electrical and Computer Engineering, Lehigh University, Bethlehem, PA 18015, USA; Center for Photonics and Nanoelectronics, Lehigh University, Bethlehem, PA 18015, USA; Bioengineering Program, Lehigh University, Bethlehem, PA 18015, USA. Electronic address:
This paper proposes a texture analysis technique that can effectively classify different types of human breast tissue imaged by Optical Coherence Microscopy (OCM). OCM is an emerging imaging modality for rapid tissue screening and has the potential to provide high resolution microscopic images that approach those of histology. OCM images, acquired without tissue staining, however, pose unique challenges to image analysis and pattern classification.
View Article and Find Full Text PDFPerianal Tumor With Overlap Features of Fibroadenoma and Phyllodes Tumor Arising From Anogenital Mammary-like Glands.
Am J Dermatopathol
August 2016
*The Ohio State University College of Medicine, Columbus, OH; and †Wexner Medical Center at Ohio State University, Division of Dermatology, Gahanna, OH.
The use of Au@SiO2 shell-isolated nanoparticle-enhanced Raman spectroscopy for human breast cancer detection.
Anal Bioanal Chem
September 2014
Department of Breast Surgery, The First Hospital of Jilin University, Changchun, 130021, China.
This study uses the powerful fingerprint features of Raman spectroscopy to distinguish different types of breast tissues including normal breast tissues (NB), fibroadenoma (FD), atypical ductal hyperplasia (ADH), ductal carcinoma in situ (DCIS), and invasive ductal carcinoma (IDC). Thin frozen tissue sections of fresh breast tissues were measured by Raman spectroscopy. Due to the inherent low sensitivity of Raman spectra, Au@SiO2 shell-isolated nanoparticle-enhanced Raman spectroscopy (SHINERS) technique was utilized to provide supplementary and more informative spectral features.
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