Microfluidic flow rate detection based on integrated optical fiber cantilever.

Lab Chip

Rowland Institute, Harvard University, 100 Edwin H. Land Blvd, Cambridge, MA 02142, USA.

Published: October 2007

We demonstrate an integrated microfluidic flow sensor with ultra-wide dynamic range, suitable for high throughput applications such as flow cytometry and particle sorting/counting. A fiber-tip cantilever transduces flow rates to optical signal readout, and we demonstrate a dynamic range from 0 to 1500 microL min(-1) for operation in water. Fiber-optic sensor alignment is guided by preformed microfluidic channels, and the dynamic range can be adjusted in a one-step chemical etch. An overall non-linear response is attributed to the far-field angular distribution of single-mode fiber output.

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Source
http://dx.doi.org/10.1039/b706944hDOI Listing

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