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Article Synopsis
  • Buerger's disease (BD) is a serious condition that requires early diagnosis for effective treatment, but there’s no universally accepted method for diagnosing it due to varied criteria used by different vascular centers.
  • A recent Delphi Consensus Study highlighted the lack of consensus on BD diagnostic criteria, particularly beyond the requirement of a history of smoking, making it hard to compare patient outcomes globally.
  • The VAS-European Independent Foundation has proposed that a definitive BD diagnosis should include a history of smoking, typical angiographic and histopathological features, and suggests using a combination of major and minor criteria for suspected diagnoses, with validation studies currently in progress.
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User interaction has the potential to greatly facilitate the exploration and understanding of 3D medical images for diagnosis and treatment. However, in certain specialized environments such as in an operating room (OR), technical and physical constraints such as the need to enforce strict sterility rules, make interaction challenging. In this paper, we propose to facilitate the intraoperative exploration of angiographic volumes by leveraging the motion of a tracked surgical pointer, a tool that is already manipulated by the surgeon when using a navigation system in the OR.

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Outcome of Treatment of Uveitic Macular Edema: The Multicenter Uveitis Steroid Treatment Trial 2-Year Results.

Ophthalmology

November 2015

Department of Epidemiology, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland; Departments of Ophthalmology and Medicine, the Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:

Purpose: To evaluate the 2-year outcomes of uveitic macular edema.

Design: Longitudinal follow-up of a randomized cohort.

Participants: At baseline, 148 eyes of 117 patients enrolled in the Multicenter Uveitis Steroid Treatment (MUST) Trial had macular edema, and 134 eyes of 108 patients completed 2-year follow-up.

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Rationale And Objectives: The aim of this study was to compare conventional two-dimensional (2D) digital subtraction angiography (DSA) with three-dimensional (3D) rotational DSA in the investigation of intracranial aneurysm in terms of detection, size measurement, neck diameter, neck delineation, and relationship with surrounding vessels. A further aim was to compare radiation dose, contrast volume, and procedural time between the two protocols.

Materials And Methods: Thirty-five patients who presented with subarachnoid bleeds on computed tomography and were suspected of having intracranial aneurysms underwent conventional 2D DSA followed by 3D DSA.

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The effective visualization of vascular structures is critical for diagnosis, surgical planning as well as treatment evaluation. In recent work, we have developed an algorithm for vessel detection that examines the intensity profile around each voxel in an angiographic image and determines the likelihood that any given voxel belongs to a vessel; we term this the "vesselness coefficient" of the voxel. Our results show that our algorithm works particularly well for visualizing branch points in vessels.

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