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Prenatal exposure to an environmentally relevant phthalate mixture alters oxidative stress, apoptosis, cell cycle regulators, and steroidogenic factors in the ovaries of F1 mice.
Reprod Toxicol
March 2025
Department of Comparative Biosciences, University of Illinois Urbana-Champaign, Urbana, IL 61802, USA. Electronic address:
Phthalates are synthetic chemical compounds found in consumer products and known endocrine-disrupting chemicals. However, it is not well known if prenatal exposure to phthalate mixtures can affect reproductive health in female offspring. Thus, this study tested the hypothesis that prenatal exposure to an environmentally relevant phthalate mixture disrupts long-term ovarian function in adult F1 mice.
View Article and Find Full Text PDFAdverse birth outcome and associated factors among mothers with antepartum hemorrhage in public hospitals Tigray, northern Ethiopia, 2020.
BMC Pregnancy Childbirth
January 2025
College of Health Science, School of nursing, Mekelle University, Mekelle, Ethiopia.
Background: Adverse birth outcome is a major public health problem in the world and in Ethiopia. Antepartum hemorrhage complicates 3-5% of pregnancies and is a primary cause of perinatal and maternal mortality worldwide. One in five of all preterm babies are born in association with antepartum hemorrhage.
View Article and Find Full Text PDFAcute respiratory tract infections during the first 6 years of life - results from the German birth cohort study LoewenKIDS.
Int J Infect Dis
January 2025
Institute of Medical Epidemiology, Biometrics, and Informatics, Interdisciplinary Centre for Health Sciences, Medical Faculty of the Martin Luther University Halle-Wittenberg, Halle (Saale), Germany; Helmholtz Centre for Infection Research, Epidemiology Research Group Epidemiological and Statistical Methods, Braunschweig, Germany. Electronic address:
Objectives: Acute respiratory tract infections (ARIs) often occur in early childhood and are mostly self-limited. However, they impose a high socioeconomic burden and can be associated with chronic diseases later in life. To date, data on self-reported ARIs beyond infancy are limited.
View Article and Find Full Text PDFNasal microbial diversity is associated with survival in piglets infected by a highly virulent PRRSV-1 strain.
Anim Microbiome
January 2025
Department of Animal Health and Anatomy, Universitat Autònoma de Barcelona, Travessera dels Turons s/n, 08193, Cerdanyola del Vallès, Spain.
Background: Porcine reproductive and respiratory syndrome virus (PRRSV) is a major threat to swine industry worldwide, especially virulent variants arising during the last years, such as Spanish PRRSV-1 Rosalia strain. The role of the nasal microbiota in respiratory viral infections is still to be unveiled but may be promisingly related with the health status of the animals and thus, their susceptibility. The goal of this project was to study the nasal microbiota composition of piglets during a highly virulent PRRSV-1 outbreak comparing animals that died due to the infection with animals that survived it.
View Article and Find Full Text PDFNutritional Changes to Improve Female Fertility: Role of Obesity, Hormones, Dietary Patterns and Endocrine Disrupting Chemicals.
Obstet Gynecol Surv
January 2025
Professor, Department of Biochemistry and Molecular Biology-A, University of Murcia, Murcia, Spain.
Importance: Infertility affects around 180 million people in the world and can be influenced by a number of nutritional factors.
Objective: The idea of a pretreatment optimization including beneficial weight loss, adequate physical activity, and good lifestyle habits could enhance fertility for many couples who want to conceive a baby.
Results: There are different aspects related to nutrition, such as obesity (affecting 23%-30% of reproductive-aged women), dietary patterns (type of diet, good or bad habits, and physical activity), nutrients (vitamins or minerals), hormones (adipokines, among others), and endocrine-disrupting chemicals (phytoestrogens and bisphenol A, among others) that have a clear impact on women's fertility.
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