We have fabricated robust nanosurgical needles suitable for single cell operations by modifying multiwalled carbon nanotube (MCNT)-terminated atomic force microscopy (AFM) tips. Extra-long MCNT AFM tips were prepared and fortified with molecular layers of carbon to overcome mechanical instabilities and then coated with an outer shell of gold to promote chemical versatility. The terminal diameters of the final fabricated tips were approximately 30-40 nm, and the MCNT probes were several micrometers in length. We illustrate the capability of these modified MCNT tips to carry nanoparticulate payloads and to penetrate the plasma membrane of living pleural mesothelial cells at the smallest indentation depths (100-200 nm) and lowest penetration forces (100-200 pN) currently reported for these procedures.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/la701878n | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Mathematical model and stability of SWCNT- and MWCNT-based nanofluid flow with thermal and chemically reactive effects inside a porous vertical cone.
Front Chem
January 2025
Department of Mathematics and Statistics, Hazara University, Mansehra, Pakistan.
This study investigates the significance of single-walled (SWCNTs) and multi-walled (MWCNTs) carbon nanotubes with a convectional fluid (water) over a vertical cone under the influences of chemical reaction, magnetic field, thermal radiation and saturated porous media. The impact of heat sources is also examined. Based on the flow assumptions, the fundamental flow equations are modeled as partial differential equations (PDEs).
View Article and Find Full Text PDFFluctuation-induced extensive molecular transport modulation of interaction strength.
Phys Chem Chem Phys
January 2025
Department of Chemistry, Hankuk University of Foreign Studies, Yongin 17035, Republic of Korea.
In our previous work, we studied the thermodynamics of two cases of intercompartmental transport through a carbon nanotube: one involving water molecules and the other involving nonpolar molecules. Free energy calculations indicate that transporting water molecules from one compartment to another a narrow channel is impossible, whereas for nonpolar molecules, only approximately half can be transported. Therefore, the interaction strength between transported molecules significantly affects molecular transport.
View Article and Find Full Text PDFLaser ablation propulsion is an important micro-propulsion system for microsatellites. Polymers with carbon added and carbon-based nanomaterial have been demonstrated as propellants with high impulse coupling coefficient (C). Among them, the carbon nanotube film exhibits a low ablation threshold fluence of 25 mJ/cm, which shows its potential for propulsion under low laser fluence.
View Article and Find Full Text PDFPutrescine is a kind of physical diamine that is closely related to food deterioration and food quality safety. This study employs a novel fiber optic biosensor based on S-tapered and waist extension techniques, as well as localized surface plasmon resonance (LSPR), to detect putrescine accurately. The gold nanoparticles (AuNPs) are fixed on the fiber to excite LSPR.
View Article and Find Full Text PDFAnisotropic hydrogel microelectrodes for intraspinal neural recordings in vivo.
Nat Commun
January 2025
Department of Biomedical Engineering, State University of New York at Binghamton, Binghamton, NY, 13902, USA.
Creating durable, motion-compliant neural interfaces is crucial for accessing dynamic tissues under in vivo conditions and linking neural activity with behaviors. Utilizing the self-alignment of nano-fillers in a polymeric matrix under repetitive tension, here, we introduce conductive carbon nanotubes with high aspect ratios into semi-crystalline polyvinyl alcohol hydrogels, and create electrically anisotropic percolation pathways through cyclic stretching. The resulting anisotropic hydrogel fibers (diameter of 187 ± 13 µm) exhibit fatigue resistance (up to 20,000 cycles at 20% strain) with a stretchability of 64.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!