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Leptospirosis manifested with severe pulmonary hemorrhagic syndrome successfully treated with veno-venous extracorporeal membrane oxygenation: A case report and literature review.
Medicine (Baltimore)
December 2024
Department of Critical Care Medicine, Fuyang Infectious Disease Clinical College of Anhui Medical University, Fuyang, Anhui Province, China.
Rationale: The mortality rate associated with pulmonary hemorrhage induced by leptospirosis is notably high. Available treatment modalities are limited, and their efficacy has not been fully demonstrated. Here, we present the case report of a patient with leptospirosis-induced pulmonary hemorrhagic syndrome.
View Article and Find Full Text PDFTriple Co-infection With Salmonella typhi, Leptospira, and Campylobacter coli in a Patient From Guayaquil, Ecuador: Clinical and Diagnostic Challenges.
Cureus
November 2024
Medicine, University of Guayaquil, Guayaquil, ECU.
This case report describes the unusual presentation of a 32-year-old male from Guayaquil, Ecuador, who was diagnosed with a rare triple infection caused by , , and . The patient presented with persistent high fever, severe gastrointestinal symptoms, abdominal pain, and jaundice, following the consumption of street food in a resource-limited area. Important clinical findings included hepatosplenomegaly and elevated liver enzymes, which initially complicated the differential diagnosis.
View Article and Find Full Text PDFEpidemiological trends and clinical characteristics of human leptospirosis in Wenzhou, Zhejiang Province, China, 2020-2022.
J Infect Dev Ctries
November 2024
Department of Infectious Diseases, Wenzhou Central Hospital, Wenzhou, Zhejiang, China.
Article Synopsis
- The study aimed to analyze the clinical characteristics and trends of human leptospirosis in Wenzhou, China, from 2020 to 2022 to better inform prevention and control measures.
- A total of 41 cases were reported during this period, with the highest incidence in 2021 and a notable concentration of cases occurring in the late summer to fall, primarily affecting males in the farming sector.
- The findings indicate a moderate level of leptospirosis incidence, emphasizing the need for improved monitoring of host animals and populations to prevent future outbreaks.
Predicting Leptospirosis Using Baseline Laboratory Tests and Geospatial Mapping of Acute Febrile Illness Cases Through Machine Learning-Based Algorithm.
Cureus
November 2024
Pharmacology, All India Institute of Medical Sciences, Kalyani, IND.
Introduction Leptospirosis is a zoonotic infection caused by bacteria, which is reemerging in various regions and often poses a diagnostic challenge due to its nonspecific symptoms. While most infections are mild, severe cases occur in 5-10% of patients and are associated with high mortality, especially in areas with poor sanitation and urbanization. This study aims to investigate the association of specific parameters with leptospirosis diagnosis using a machine learning model and geographic mapping tools to identify spatial patterns and high-risk areas for the disease.
View Article and Find Full Text PDFA Rare Case of Weil's Disease Presenting With Severe Hyperbilirubinemia and Acute Kidney Injury: A Diagnostic Challenge in Urban England.
Cureus
November 2024
Internal Medicine, Northumbria Healthcare NHS Trust, Newcastle-Upon-Tyne, GBR.
We present a rare and challenging case of Weil's disease in a patient who was admitted to the Critical Care Unit with a clinical suspicion of the condition. The patient showed a prompt response to treatment before laboratory confirmation was obtained. Leptospirosis, a zoonotic disease, is most commonly found in tropical and temperate regions.
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