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This article presents a clinical case of ocular thrombotic microangiopathy of mixed origin (antiphospholipid syndrome, malignant arterial hypertension, multigenic thrombophilia). Multimodal imaging of the fundus provides a detailed assessment of its structures. Pathological changes in the choroid, the "retinal pigment epithelium - Bruch's membrane" complex, and the neurosensory retina, identified using fundus photography, short-wavelength autofluorescence, optical coherence tomography (OCT), and OCT angiography, are described as nonspecific in nature.
View Article and Find Full Text PDFPresumed Choroidopathy of IgG4-Related Disease Discovered During 16-Year Follow-Up of a Patient With Polycystic Kidney Disease.
Cureus
October 2024
Nephrology, Okayama University Hospital, Okayama City, JPN.
Immunoglobulin G4 (IgG4)-related disease is characterized by infiltration with IgG4-producing plasma cells in different organs and the elevation of serum IgG4. We present a patient with polycystic kidney disease in long-term follow-up who developed bilateral lacrimal gland enlargement and presumed IgG4-related choroidopathy at different time points. A 45-year-old woman developed bilateral upper eyelid swelling.
View Article and Find Full Text PDFAtypical Presentation of Vitreous Inflammation in a Patient With Hypertensive Retinopathy.
J Vitreoretin Dis
July 2024
Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.
To describe an atypical presentation of vitreous inflammation in a patient with malignant hypertension. A case was evaluated. A patient presenting with a hypertensive emergency was found to have decreased vision in the setting of severe optic nerve head edema, extensive hard exudates, cotton-wool spots, and Elschnig spots in both eyes secondary to malignant hypertension as well as vitreous cells bilaterally.
View Article and Find Full Text PDFMultiple Bilateral Retinal Pigment Epithelial Detachments in a Patient with Systemic Lupus Erythematosus: A Case Report.
J Curr Ophthalmol
March 2024
Department of Ophthalmology, State University of Campinas (Unicamp), Campinas, São Paulo, Brazil.
Article Synopsis
- A 28-year-old woman with systemic lupus erythematosus (SLE) experienced blurred vision and was hospitalized due to worsening renal function and high blood pressure.
- During her hospital stay, eye examinations revealed multiple bilateral retinal pigment epithelial detachments (PEDs) and other retinal changes, likely linked to her SLE and other health conditions.
- After treatment with corticosteroids and antihypertensives, her vision improved, though no significant retinal changes were observed, highlighting the complex nature of ocular issues associated with SLE.
Choroidopathy and Retinal Detachment: A Rare Sighting in a Case of Postpartum Hemorrhage Presenting With Posterior Reversible Encephalopathy Syndrome.
Cureus
December 2023
Department of General Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Health Education and Research, Wardha, IND.
Posterior reversible encephalopathy syndrome (PRES) is a rare syndrome characterized by convulsions, headache, fatigue, impaired mental status, and decreased vision. It is mainly accompanied by hypertension. Although the pathophysiology of PRES is unknown, some theories revolve around cerebral autoregulation, the ability to maintain cerebral blood flow, or the brain's ability to maintain steady cerebral blood flow over a varying range of blood pressures by cerebral vaso-constriction or dilation.
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