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Innovative biopolymers composite based thin film for wound healing applications.
Sci Rep
November 2024
Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Efficient wound and burn healing is crucial for minimising complications, preventing infections, and enhancing overall well-being, necessitating the development of innovative strategies. This study aimed to formulate a novel thin film combining chitosan, carboxymethyl cellulose, tannic acid, and beeswax for improved wound healing applications. Several formulations, incorporating chitosan, carboxymethyl cellulose, tannic acid, and beeswax in various percentages, were utilized to deposit thin films via the solvent evaporation technique, Mechanical properties, morphology, antioxidant activity, antibacterial efficacy, and wound healing potential were evaluated.
View Article and Find Full Text PDFInfluence of copper ion cross-linked CMC-PVA film on cell viability and cell proliferation study.
Int J Biol Macromol
December 2024
Chemical Engineering Group and Centre for Petroleum Research, CSIR-North East Institute of Science and Technology, Jorhat, Assam 785006, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh 201002, India. Electronic address:
Article Synopsis
- The study involves creating films using carboxymethyl cellulose and polyvinyl alcohol, with citric acid as a cross-linking agent and glycerol as a plasticizer.
- Cross-linking with cupric chloride at varying concentrations and times reduced elasticity but increased the films' antibacterial properties against common bacteria.
- The findings suggest these films could potentially be used for treating second-degree burn wounds, highlighting their effectiveness, cell attachment, and water vapor permeability.
Synthesis and evaluation of cross-linked tragacanthin nanofibers as implants for delivery of cisplatin to hepatocellular carcinoma.
Heliyon
September 2024
Health Physics Division, PINSTECH, P.O. Nilore, Islamabad, Pakistan.
There is growing interest in the use of electrospun polymeric nanofibers in drug delivery systems due to their remarkable surface-to-volume ratio, which enhances the processes of drug loading, specific cell binding and proliferation. The preferred polymers for drug delivery must be biocompatible and biodegradable. Gum tragacanth is one of the materials of choice for drug delivery.
View Article and Find Full Text PDFBiopolymeric Insulin Membranes for Antimicrobial, Antioxidant, and Wound Healing Applications.
Pharmaceutics
July 2024
Departamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico.
Delayed wound healing increases the wound's vulnerability to possible infections, which may have lethal outcomes. The treatments available can be effective, but the urgency is not fully encompassed. The drug repositioning strategy proposes effective alternatives for enhancing medical therapies for chronic diseases.
View Article and Find Full Text PDFEssential oils loaded carboxymethylated Cassia fistula gum-based novel hydrogel films for wound healing.
Int J Biol Macromol
October 2024
Department of Applied Chemistry, Delhi Technological University, Delhi, India. Electronic address:
Carboxymethylated Cassia fistula gum (CCFG) and citric acid (CA) based wound healing film, (CCFG-CA) was developed using the solvent casting method. Glycerol was added as a plasticizing agent. The synthesized Carboxymethylated Cassia fistula gum cross-linked citric acid based hydrogel film (CCFG-CA) was evaluated morphologically, thermally, and structurally using FESEM, TGA, XRD and FTIR.
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