This paper describes the clinical, radiological and cytomorphological findings of tumoral calcinosis in a twelve-year old boy with normal serum calcium levels and simultaneous involvement of the right shoulder and the left hip. The aim of presentation is to highlights the fact that clinicoradiological correlation and correct interpretation of cytologic findings can alleviate patients' anxiety and avoid unnecessary mutilating surgery in this uncommon but completely benign condition.
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Ren Fail
December 2025
Department of Nephrology, Chengyang District People's Hospital, Qingdao, China.
Background: Vascular calcification is common and progressive in patients with chronic kidney disease. However, the risk factors associated with the progression of vascular calcification in patients receiving maintenance dialysis have not been fully elucidated. Here, we aimed to evaluate vascular calcification and identify the factors associated with its progression in patients receiving maintenance hemodialysis.
View Article and Find Full Text PDFInt J Mol Sci
January 2025
Research Direction, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano No. 1, Col. Sección XVI, Mexico City 14080, Mexico.
Deregulation of micro-RNAs (miRNAs) may contribute to mechanisms of injury in the bicuspid aortic valve (BAV). Our objective was to investigate the expression of miRNAs in aortic tissue from patients who underwent aortic valve replacement for aortic stenosis and its relationship with aortic dilatation. The study included 78 patients, 40 with bicuspid aortic valve (BAV) and 38 with tricuspid aortic valve (TAV).
View Article and Find Full Text PDFInt J Mol Sci
January 2025
Department of Experimental Medicine, TOR, University of Rome "Tor Vergata", 00133 Rome, Italy.
The aim of this work was to explore the biomarkers associated with epithelial to mesenchymal transition (EMT) and mineralization processes as new prognostic factors across different breast cancer phenotypes. To this end, 133 breast biopsies, including benign and malignant lesions, with or without microcalcifications, were retrospectively collected. Immunohistochemical analysis was performed to evaluate the expression of vimentin, BMP-2, BMP-4, RANKL, Runx2, OPN, PTX3, and SDF-1, while Kaplan-Meier plots were used to assess their prognostic impact on overall survival in a dataset of 2976 breast cancer patients.
View Article and Find Full Text PDFMedicina (Kaunas)
December 2024
Department of Respiratory Disease, Cukurova University Faculty of Medicine, Yüreğir, Adana 01250, Turkey.
: This study investigates the prevalence of calcification in mediastinal lymph nodes among sarcoidosis patients and the influencing factors. Sarcoidosis is a multisystemic inflammatory disease characterized by non-caseating epithelioid granulomas. Bilateral hilar lymphadenopathy (LAP) is the most common radiographic finding, with studies showing a correlation between the frequency of lymph node calcification and disease duration, with a frequency of 3% relating to a duration of 5 years and a frequency of 20% relating to one of 10 years.
View Article and Find Full Text PDFJ Cardiothorac Surg
January 2025
Department of Cardiothoracic Surgery, Mayo Clinic, Jacksonville, FL, USA.
Mitral and aortic annular calcification is an age-related degenerative process that can result in severe mitral and/or aortic stenosis and/or regurgitation. Annular calcification not only increases the surgical complexity but also increases the risk of complications. In this case report, we present the innovative use of the Sonopet ultrasonic surgical aspirator for aortic and mitral annular decalcification in a patient with hypertrophic obstructive cardiomyopathy, mild aortic stenosis and moderate mitral regurgitation in the presence of mitral annular calcification (MAC) and aorto-mitral curtain calcification.
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