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Alcohol Use Disorder Medication Coverage and Utilization Management in Medicaid Managed Care Plans.
JAMA Netw Open
March 2025
Department of Health Law, Policy and Management, Boston University School of Public Health, Boston, Massachusetts.
Importance: Evidence-based, patient-centered treatment for alcohol use disorder (AUD) can include pharmacotherapy with naltrexone, acamprosate, or disulfiram; however, these medications are rarely used. Medicaid managed care plans (MCPs) manage health services for nearly 80% of Medicaid enrollees and are the largest payer for addiction treatment services. Little is known about Medicaid MCP policies for AUD medications.
View Article and Find Full Text PDFMultiple cardioembolic attacks with a huge ventricular thrombus in dilated cardiomyopathy: A case report and comprehensive review.
J Int Med Res
March 2025
Healthy Heart Research Center, Heshmat Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Left ventricular thrombus is one of the major complications of dilated cardiomyopathy. Although the presence of a cardiac thrombus is a major risk factor for embolization, several probable conditions, the connection of which is not thoroughly studied, such as gout disease and methamphetamine abuse, are also possible causes. We present the case report of a male in his early 40s with a history of alcohol and methamphetamine abuse, gout, and dilated cardiomyopathy, experiencing multiple ischemic attacks, including acute limb ischemia, dysarthria, and renal infarct.
View Article and Find Full Text PDFUnderstanding Personalized Dynamics in Eating Disorders: A Dynamic Time Warp Analysis.
Int J Eat Disord
March 2025
Rivierduinen Eating Disorders Ursula, Leiden, the Netherlands.
Objective: To enhance our understanding of the processes of change and the interaction of symptoms, we applied a relatively novel method known as Dynamic Time Warp to data from low-threshold internet-based interventions directed at decreasing eating disorder (ED) symptoms and increasing help-seeking.
Method: Utilizing data from the Featback study, we examined how various factors such as ED psychopathology, binge eating, vomiting, laxative use, BMI, anxiety, depression, self-efficacy, social support, well-being, and health-related quality of life interplayed over a period of 14 months among 355 individuals at six different time points. Moreover, we explored which symptoms exerted a significant temporal relationship on others (with high out-strength) and which were most affected by other symptoms (with high in-strength).
Opioid withdrawal syndrome induced by naldemedine administration in a cancer patient without brain metastasis.
Palliat Support Care
March 2025
Departments of Psycho-oncology, Saitama Medical University International Medical Center, Saitama, Japan.
Objectives: Naldemedine is a peripherally acting μ-opioid receptor antagonist used to treat opioid-induced constipation. As this drug does not cross the blood-brain barrier, it is believed that patients without brain metastases do not experience opioid withdrawal symptoms.
Methods: Here, we experienced a case in which a cancer patient without brain metastasis presented with anxiety and restlessness that was severe enough to interfere with daily life.
Serotonin Syndrome Associated With High-dose Diphenhydramine Use Complicating Abdominoplasty and Mastopexy.
Plast Reconstr Surg Glob Open
March 2025
Department of Surgery, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Chappaqua, NY.
Serotonin syndrome is a condition associated with increased serotonergic transmission in the central nervous system. Although shortfalls with diagnostic criteria have led to misleading associations with multiple medications, a possible precipitant is diphenhydramine. Documentation of such an association would prove important for physician practice, as diphenhydramine remains one of the most popular antihistamines available.
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