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Article Synopsis
  • Brucellosis is a rare but challenging disease to diagnose, especially when it involves the joints, and should be considered in patients with prolonged fever and joint pain.
  • A case study of a 41-year-old goat farmer highlighted her symptoms of low back and joint pain lasting four months, leading to a diagnosis confirmed by serological tests.
  • Early detection and treatment, including NSAIDs and antibiotics, resulted in complete symptom relief within four weeks, emphasizing the importance of detailed history and physical exams in diagnosing atypical cases.
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Infectious spondylodiscitis is a life-threatening disease and has some challenges in terms of diagnostic, differentiative, and therapeutic processes. Therefore, rapid and effective management of infectious spondylodiscitis is necessary. Hematological inflammation indices (HIIs) such as the neutrophil/lymphocyte ratio and aggregate index of systemic inflammation are derived from blood cells and used as diagnostic, prognostic, predictive, and treatment monitoring indicators.

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Can Hematological Inflammatory Indices Be Used to Differentiate Modic Type 1 Changes from Brucella Spondylodiscitis?

Medicina (Kaunas)

July 2024

Department of Infectious Diseases and Clinical Microbiology, Medical Faculty, Van Yüzüncü Yıl University, Van 65090, Turkey.

Article Synopsis
  • This study investigates the differences between brucella spondylodiscitis, an infectious condition, and Modic type I changes (MC1), a non-infectious condition, using hematological inflammatory indices (HII) as potential diagnostic tools.
  • A total of 35 patients with brucella spondylodiscitis and 37 with MC1 were analyzed, revealing that while the two groups were similar in various blood parameters, the brucella group had significantly lower pain duration, higher CRP and ESR levels, and lower platelet counts.
  • The research found that HII such as neutrophil to lymphocyte ratio showed no significant differences between the groups, suggesting that
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Article Synopsis
  • The study explored how common eye issues are in patients with brucellosis and how well they responded to treatment.
  • Out of 242 patients, 24.8% experienced eye problems, with conjunctivitis being the most frequent, followed by uveitis.
  • Most patients showed improvement in their eye symptoms over time, highlighting the importance of early eye exams in brucellosis treatment.
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The first human case report of molecularly confirmed co-infection of and A case report.

Heliyon

April 2024

Division of Infectious Diseases, Department of Medicine, Faculty of Medicine, Chulalongkorn University, And King Chulalongkorn Memorial Hospital, Thai Red Cross Society, 1873, Rama IV Road, Pathum Wan, Bangkok, 10330, Thailand.

Co-infection with and has been rarely reported. To date, there are only two co-infection case reports from Croatia and China which diagnosed the infections mainly through the use of serological tests. In this report, we present the first case of molecularly confirmed bacteremia and spondylodiscitis co-infection in a goat dairy farmer who presented with lumbosacral spondylodiscitis and bilateral psoas abscesses.

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