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Differential TLR2 and TLR4 mediated inflammatory and apoptotic responses in asymptomatic and symptomatic Leptospira interrogans infections in canine uterine tissue.
Microb Pathog
January 2025
Department of Physiology, Faculty of Veterinary Medicine, Atatürk University, Erzurum, Turkey; Department of Biochemistry, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
Leptospirosis is major zoonotic disease with global implications, affecting both domestic animals and humans. It is caused by Leptospira interrogans (L. interrogans), which can damage multiple organs, including the kidneys, liver, testes, and uterus.
View Article and Find Full Text PDFSeroprevalence and associated risk factors for bovine leptospirosis in Egypt.
Sci Rep
February 2024
Department of Biomedical Physics, Medical Research Institute, Alexandria University, Alexandria, Egypt.
Leptospirosis is caused by pathogenic bacteria of the genus Leptospira and is one of causative agents of reproductive problems leading to negative economic impact on bovine worldwide. The goal of this study was to investigate the seroprevalence of Leptospira spp. in cattle in some governorates of Egypt's Nile Delta and assess the risk factors for infection.
View Article and Find Full Text PDFUnraveling the leptospirosis epidemic: tales from the Philippine outbreak - a short communication.
Ann Med Surg (Lond)
February 2024
St. Luke's aurora hospital, Milwaukee, Wisconsin.
Leptospirosis, also known as Weil's disease, is an emerging zoonotic infection that occurs worldwide but is particularly common in the tropics. There has been an increasing trend of leptospirosis in the Philippines since the outbreak occurred in 2020. The number of reported cases was 182 in 2020, 1661 in 2021, and 2794 in 2022.
View Article and Find Full Text PDFEvaluating the Antimicrobial and Anti-Hemolytic Activity of Synthesized Pseudopeptide against Species: In Silico and In Vitro Approach.
Molecules
January 2023
Department of Biotechnology and Bioinformatics, JSS Academy of Higher Education and Research, Mysuru 570 015, India.
Bacterial infections are one of the leading causes of morbidity, mortality, and healthcare complications in patients. Leptospirosis is found to be the most prevalent, re-emergent, and neglected tropical zoonotic disease worldwide. The adaptation to various environmental conditions has made acquire a large genome (~4.
View Article and Find Full Text PDFAn Overview of Anthropogenic Actions as Drivers for Emerging and Re-Emerging Zoonotic Diseases.
Pathogens
November 2022
Postgraduate Program in Animal Bioscience, Federal Rural University of Pernambuco (UFRPE), Recife, Pernambuco 52171-900, Brazil.
Population growth and industrialization have led to a race for greater food and supply productivity. As a result, the occupation and population of forest areas, contact with wildlife and their respective parasites and vectors, the trafficking and consumption of wildlife, the pollution of water sources, and the accumulation of waste occur more frequently. Concurrently, the agricultural and livestock production for human consumption has accelerated, often in a disorderly way, leading to the deforestation of areas that are essential for the planet's climatic and ecological balance.
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