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Patent foramen ovale and migraine: a cross-sectional study from the Northern Manhattan Study (NOMAS).
Circulation
September 2008
Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
Background: A causal relationship between patent foramen ovale (PFO) and migraine has been hypothesized, and improvement of migraine frequency and severity after percutaneous PFO closure has been reported. Population-based data on the relationship between PFO and migraine are sparse, however. The objective of this study was to examine the association between PFO and migraine among stroke-free individuals in an urban, population-based, multiethnic cohort.
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