A case of reconstruction after first metacarpal resection by reversed free vascularized osteocutaneous pedis flap is presented. This procedure avoids bone resorption and preserves the trapezio metacarpal joint contrary to conventional bone graft. A double rotation is applied to the flap: the head of the metatarsal becomes proximal and the palmar side becomes dorsal. The metacarpo-phalangeal joint undergo arthrodesis. With a follow up of three years, there is no pain, the Kapandji score is 8/10 (very good range of motion), there is no osteoarthritis.
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http://dx.doi.org/10.1016/j.main.2007.07.004 | DOI Listing |
Acc Chem Res
January 2025
Helmholtz Institute Ulm (HIU) Electrochemical Energy Storage, Helmholtzstrasse 11, 89081 Ulm, Germany.
ConspectusLithium-ion batteries (LIBs) based on graphite anodes are a widely used state-of-the-art battery technology, but their energy density is approaching theoretical limits, prompting interest in lithium-metal batteries (LMBs) that can achieve higher energy density. In addition, the limited availability of lithium reserves raises supply concerns; therefore, research on postlithium metal batteries is underway. A major issue with these metal anodes, including lithium, is dendritic formation and insufficient reversibility, which leads to safety risks due to short circuits and the use of flammable electrolytes.
View Article and Find Full Text PDFBiochim Biophys Acta Mol Basis Dis
January 2025
Department of Urology, Urology Research Institute, the First Affiliated Hospital, Fujian Medical University, Fuzhou 350005, China; Fujian Key Laboratory of Precision Medicine for Cancer, the First Affiliated Hospital, Fujian Medical University, Fuzhou 350005, China. Electronic address:
Objective: The aim of this work is to identify putative hub genes for the advancement of clear cell renal cell carcinoma (ccRCC) and determine the fundamental mechanisms.
Methods: We employed multiple bioinformatics techniques to screen hub genes. Key hub gene expression levels in ccRCC were assessed.
Nano Lett
January 2025
School of Chemical Engineering and Technology, State Key Laboratory of Chemical Engineering, International Joint Laboratory of Low-carbon Chemical Engineering of Ministry of Education, Tianjin University, Tianjin 300072, P. R. China.
Molybdenum disulfide (MoS) is a promising anode for sodium-ion batteries (SIBs) due to its high theoretical capacity and layered structure. However, a poor reversible conversion reaction and a low initial Coulombic efficiency (ICE) limit its practical application. This study systematically investigated the potential of pre-intercalated sodium ions molybdenum disulfide (Na-MoS) as an anode material for SIBs.
View Article and Find Full Text PDFPharmaceutics
January 2025
Department of Mathematics, Visva-Bharati University, Santiniketan 731235, WB, India.
Microneedle(MN)-based drug delivery is one of the potential approaches to overcome the limitations of oral and hypodermic needle delivery. An in silico model has been developed for hollow microneedle (HMN)-based drug delivery in the skin and its subsequent absorption in the blood and tissue compartments in the presence of interstitial flow. The drug's reversible specific saturable binding to its receptors and the kinetics of reversible absorption across the blood and tissue compartments have been taken into account.
View Article and Find Full Text PDFInt J Mol Sci
January 2025
Department of Nutrition, Faculty of Medicine, University of Chile, Santiago 8380000, Chile.
Consumption of phytosterols is a nutritional strategy employed to reduce cholesterol absorption, but recent research shows that their biological activity might go beyond cholesterol reduction for the treatment of metabolic dysfunction-associated fatty liver disease (MAFLD), and novel phytosterol formulations, such as submicron dispersions, could improve these effects. We explored the therapeutic activity of phytosterols, either formulated as submicron dispersions of phytosterols (SDPs) or conventional phytosterol esters (PEs), in a mouse model of MAFLD. MAFLD was induced in mice by atherogenic diet (AD) feeding.
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