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Mediastinal Teratoma with Nephroblastomatous Elements: Case Report, Literature Review, and Comparison with Maturing Fetal Glomerulogenic Zone/Definitive Zone Ratio and Nephrogenic Rests.
Int J Mol Sci
November 2024
Department of Pathology, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, ON K1H 8L1, Canada.
Article Synopsis
- Extrarenal teratoid Wilms' tumor (TWT) is a rare type of cancer with complex histology, making diagnosis challenging; the case discussed involves an 8-year-old girl with a mediastinal mass containing nephroblastomatous elements.
- Surgical resection revealed a mature cystic teratoma mixed with nephroblastoma, and immunohistochemical tests confirmed the diagnosis, leading to a smooth recovery for the patient.
- This case emphasizes the importance of detailed histopathological analysis in distinguishing TWT from other tumors, underlining the necessity for long-term monitoring due to potential recurrence.
A case of presacral teratoid cyst in an adult patient.
Folia Med (Plovdiv)
April 2021
Russian Medical Academy of Continuous Professional Education, Moscow, Russia.
Presacral teratoid cyst (PTC) is a congenital structural abnormality located in the pararectal area and containing tissues from different germ layers. Cases of diagnosis and treatment of PTC in adults are extremely rare and there is little information about the treatment tactics and prognosis. We describe a case of PTC in a 28-year-old woman, with a description of the diagnostic process, preoperative and postoperative management, as well as a brief review of the literature on this topic.
View Article and Find Full Text PDFPresacral malignant teratoid neoplasm in association with pathogenic DICER1 variation.
Mod Pathol
December 2019
Division of Pathology and Center for Cancer and Immunology Research, Children's National Health System, Washington, DC, USA.
We report two malignant sacrococcygeal tumors in infants that were associated with pathogenic DICER1 variation. These tumors were composed of primitive neuroepithelium, embryonal rhabdomyosarcoma, and cartilage and initially diagnosed as immature teratomas. One child developed intracranial metastasis and died.
View Article and Find Full Text PDFPrimary renal teratoma: a rare entity.
Diagn Pathol
June 2013
Department of Pathology, Hassan II University Hospital, Fez 30000, Morocco.
Unlabelled: Teratomas are neoplasms that arise from pluripotent cells and can differentiate along one or more embryonic germ lines. Renal teratoma is an exceedingly rare condition. Teratomas commonly arise in the gonads, sacrococcygeal region, pineal gland, and retroperitoneum.
View Article and Find Full Text PDFExtrarenal teratoid Wilms' tumor: two cases in unusual locations, one associated with elevated serum AFP.
Pathol Int
January 2010
Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 138-736, Korea.
Teratoid Wilms' tumor is an unusual morphological entity characterized by a classic triphasic malignancy with predominantly heterologous tissue. The authors describe two cases of teratoid Wilms' tumor with an extrarenal site: one in a 13-year-old girl with vaginal spotting (patient 1) and another in a 1-day-old girl with a sacrococcygeal mass (patient 2). The tumors were located in the vagina and coccyx, respectively.
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