AI Article Synopsis
- Post-kala-azar dermal leishmaniasis (PKDL) is a complication that can occur after treated visceral leishmaniasis (VL), particularly in Sudan and India, impacting a significant percentage of patients.
- A case study is presented of a 46-year-old patient with AIDS who developed PKDL and uveal leishmaniasis seven months after VL diagnosis, following immune recovery from HAART.
- There is a rising trend of PKDL cases in southern Europe among HIV-infected individuals who have undergone HAART and previously had VL, but the optimal treatment for these patients has yet to be established.
Article Abstract
Post-kala-azar dermal leishmaniasis (PKDL) is a complication of visceral leishmaniasis (VL) observed mainly in Sudan and India where it follows treated VL in 50% and 10% of cases, respectively. We report a 46-year-old patient with acquired immune deficiency syndrome who, 7 months after diagnosis of VL, developed PKDL and uveal leishmaniasis following HAART-induced immune recovery. In southern Europe PKDL seems to be an emerging clinical presentation among human immunodeficiency virus (HIV)-infected patients experiencing HAART-induced immune recovery after a previous diagnosis of VL. The best treatment among HIV-infected patients remains to be determined.
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| http://dx.doi.org/10.1111/j.1365-2133.2007.08157.x | DOI Listing |
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