Two rare cases of pituitary metastases from breast and kidney cancers.

Exp Clin Endocrinol Diabetes

Department of Endocrinology, Jagiellonian University, Collegium Medicum, Kopernika 17, 31-501 Krakow, Poland.

Published: September 2007

AI Article Synopsis

  • Pituitary metastases are rare but can lead to significant endocrine and neurosurgical issues, showing varied clinical symptoms.
  • The report highlights two case studies: one patient with metastatic breast cancer experienced anterior pituitary insufficiency, while the other with renal cancer showed signs of pituitary apoplexy and vision problems.
  • Neither patient exhibited diabetes insipidus, even though it's the most common symptom associated with pituitary metastatic tumors.

Article Abstract

Pituitary metastases, though very uncommon, may cause endocrine and neurosurgical problems. The clinical manifestation of such metastases is highly variable. Most of the metastatic pituitary tumours are oligosymptomatic. We report two cases of metastatic pituitary lesions. The first patient, a 52-year old female, with metastatic breast cancer, developed symptomatic anterior pituitary insufficiency. The second patient, a 46-years old female presented with signs and symptoms of pituitary apoplexy and visual impairment due to metastasis from renal cancer. None of them was diagnosed with diabetes insipidus, the most common manifestation related to pituitary metastatic mass.

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Source
http://dx.doi.org/10.1055/s-2007-981456DOI Listing

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