The surgical treatment of epidermoid carcinoma of the lip too rarely resorts to pluri-disciplinary confrontation, although all the possible techniques, i.e. surgery, curietherapy and radiation therapy, are effective. Curietherapy still is the choice method for large lesions, due to the quality of its aesthetic and functional results. The lymph node areas of N0 patients are neglected but should not be so, because the secondary evolution of an adenopathy has a poor prognosis. All the T2 and T3 patients with no general contraindication should undergo cervical exploration.
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J Stomatol Oral Maxillofac Surg
January 2025
Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, PR China. Electronic address:
Purpose: This study aimed to evaluate a chimeric flap comprising a nasolabial flap and a buccal artery myomucosal flap used to reconstruct a large defect of the lower lip.
Materials And Methods: From November 2019 to August 2022, seven patients with lower lip carcinoma underwent radical resection and reconstruction. A chimeric flap comprising a nasolabial flap and a buccal artery myomucosal flap was used to reconstruct the large defect of the lower lip.
Natl J Maxillofac Surg
November 2024
Department of Oral and Maxillofacial Surgery, Sharad Pawar Dental College and Hospital, Wardha, Maharashtra, India.
Background: Lip carcinomas account for 23.6% to 30% of tumors affecting the oral cavity. Lip reconstruction aims to achieve a competent oral sphincter with a good cosmetic appearance while avoiding microstomia.
View Article and Find Full Text PDFOral Maxillofac Surg
January 2025
Department of Dentistry, Oral Pathology, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
Purpose: Carcinogenesis is characterized by the transformation of normal cells into malignant cells. Concerning the lower lip, exposure to UV radiation is the main etiological factor associated with the development of epidermoid carcinomas and actinic cheilitis. According to the hierarchical model theory, cancer development is driven by populations of cancer stem cells.
View Article and Find Full Text PDFInt J Surg Pathol
January 2025
Department of Pathology and Forensic Medicine, Ribeirão Preto Medical School (FMRP/USP), University of São Paulo, Ribeirão Preto, SP, Brazil.
Merkel cell carcinoma (MCC) is an uncommon aggressive neoplasm, usually arising in sun-exposed skin of the head and neck. By immunohistochemistry, KRT20 and MCPyV positivity are found in about 90% and 80% of MCCs, respectively. Noteworthy, viral status in lip/oral cavity MCCs is poorly known.
View Article and Find Full Text PDFJ Stomatol Oral Maxillofac Surg
January 2025
Department of Surgery, Stomatology, Pathology, and Radiology, Bauru School of Dentistry, University of São Paulo, Alameda Octávio Pinheiro Brisolla, 9-75, Bauru, SP 17012-901 Brazil. Electronic address:
Objective: To evaluate the clinical outcomes of surgical and non-surgical treatments for actinic cheilitis (AC) over a four-decade period and to introduce a novel Clinical Index for the Treatment and Control of Actinic Cheilitis (CITC-AC) for improved patient stratification and management.
Materials And Methods: A retrospective cohort study analyzed 151 patients diagnosed with AC treated at a university clinic between 1980 and 2020. Sociodemographic, clinical, and histopathological data were collected.
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