Prior to 2000, foot-and-mouth disease (FMD) had not been observed in Mongolia since 1973; however, between April 2000 and July 2002, Mongolia reported 44 FMD outbreaks that affected cattle, sheep, goats, and camels. The objectives of this study were to describe the distributions of the 44 reported FMD outbreaks in Mongolia and to assess their spatial clustering and directions of movement. Official reports were collected to obtain the number and species of animals both affected and at risk, and the date and geographical coordinates of each outbreak. Significant global and local spatial clusters of reported FMD outbreaks were identified. Disease spread during the second epidemic moved 76 degrees northeast and the spread of the disease during the third epidemic moved 110 degrees northwest. FMD outbreaks were clustered intensely close to other FMD-positive counties. These findings can be used in the future to help plan prevention and control measures in high risk areas.
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http://dx.doi.org/10.1007/s11259-007-9018-6 | DOI Listing |
John Brooksby was an outstanding Scottish veterinary virologist who worked at the Pirbright Institute (Pirbright) for 40 years, including 16 as the institute's director. He devised quantitative methods for measuring neutralising antibodies and perfected a complement fixation test for the diagnosis, typing and strain differentiation of foot and mouth disease (FMD), especially when combined with neutralisation. He identified four of the seven types of FMD virus (FMDV) and many subtypes.
View Article and Find Full Text PDFRev Sci Tech
December 2024
Foot and mouth disease (FMD) is a highly contagious viral disease of cloven-hoofed animals. Together with other diseases highlighted in this special edition of the Scientific and Technical Review, the circulation of FMD virus in different parts of the world has shaped the work of the World Organisation for Animal Health (WOAH) over the past hundred years. In 2012, the Global Framework for the Progressive Control of Transboundary Animal Diseases, led by WOAH and the Food and Agriculture Organization of the United Nations, established a joint FMD working group and a strategy for the control of FMD.
View Article and Find Full Text PDFCell Metab
December 2024
Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian 1, 20133 Milan, Italy; IFOM ETS, the AIRC Institute of Molecular Oncology, Via Adamello 16, 20139 Milan, Italy. Electronic address:
In preclinical experiments, cyclic fasting-mimicking diets (FMDs) showed broad anticancer effects in combination with chemotherapy. Among different tumor types, triple-negative breast cancer (TNBC) is exquisitely sensitive to FMD. However, the antitumor activity and efficacy of cyclic FMD in TNBC patients remain unclear.
View Article and Find Full Text PDFVirus Res
January 2025
Department of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh. Electronic address:
Foot-and-mouth disease (FMD) is a highly contagious transboundary disease prevalent across the Asian continent, affecting both wild and domestic artiodactyls. The disease is caused by a virus belonging to the Aphthovirus genus of the Picornaviridae family which is categorized into seven serotypes: C, O, A, SAT1, SAT2, SAT3, and Asia1. The virus spreads through direct and indirect contact, including semen, meat, fomites, ingestion, and aerosols.
View Article and Find Full Text PDFAm J Physiol Heart Circ Physiol
January 2025
Division of Kinesiology, Health, and Sports Studies, Wayne State University, Detroit, Michigan, United States.
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