AI Article Synopsis
- A case of hydrops fetalis was reported where cytomegalovirus (CMV) was detected in the fetal cord blood, indicating that the hydrops was due to a CMV infection.
- Fetal ascites was managed through the removal of fluid and the administration of CMV hyperimmunoglobulin, leading to temporary improvements in the fetus's condition.
- Despite these measures and intensive care after birth, the infant ultimately did not survive, highlighting the severity of CMV infections during pregnancy and the need for thorough diagnostic testing when such infections are suspected.
Article Abstract
Reported herein is a case of hydrops fetalis in which the cord blood expressed cytomegalovirus (CMV) antigen. Fetal ascites was removed from an infected fetus with hydrops in utero and 2.5 g CMV hyperimmunoglobulin was administered into the fetal abdominal cavity at 28 weeks gestation. After immunoglobulin administration, fetal ascites vanished, preload index of the inferior vena cava decreased and platelet count of the infant increased. However, despite intrauterine therapy and intensive neonatal care, the infant died soon after birth. The expression of CMV antigen in the nucleus of polymorphonuclear leukocytes in fetal cord blood indicated that the fetal hydrops was caused by CMV infection. When symptomatic CMV infection of a fetus is suspected from serological and ultrasound findings, further examinations should be performed for the diagnosis. Intrauterine immunoglobulin therapy could be one of the therapeutic options for the affected fetus.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/j.1447-0756.2007.00637.x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!