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PET Reporter Probes for Brain Imaging of Transduced Gene and Cell Expression: Status and Challenges.
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Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, 20892 United States.
Gene therapy and cell transduction are gaining interest as therapeutic strategies for neurological and psychiatric disorders. Positron emission tomography (PET) has been established as a uniquely powerful modality for brain molecular imaging in vivo. The utility of PET depends on the development and application of suitably specific radiotracers and/or reporter probes.
View Article and Find Full Text PDFAbsorption-Emission Codes for Atomic and Molecular Quantum Information Platforms.
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View Article and Find Full Text PDFPrediction of energy consumption in four sectors using support vector regression optimized with genetic algorithm.
Heliyon
January 2025
Department of Electrical and Electronic Engineering, Bangladesh University of Business and Technology, Dhaka-1216, Bangladesh.
Effectively managing and optimizing energy resources to accommodate population growth while minimizing carbon emissions has become increasingly intricate. A proficient approach to this dilemma is accurately predicting energy usage and emissions across diverse sectors. This paper unveils a genetic algorithm (GA)-optimized support vector regression (SVR) model designed to (i) predict electricity generation, (ii) predict energy consumption in four primary sectors-residential, industrial, commercial, and agricultural, and (iii) estimate sector-specific carbon emissions.
View Article and Find Full Text PDFConnecting changes in emissions to air quality is critical for evaluating the effects of a specific policy. Here, we introduce a methodology to aid in assessing the air quality impacts of changes in the energy system. A set of widely varying scenarios that describe alternative potential evolutions of the US energy system is constructed using the TIMES energy system model.
View Article and Find Full Text PDFStimuli-responsive benzothiazole-phenothiazine derivatives: mechanochromism, AIE, acid sensing, and anticancer efficacy in benzo[]pyrene-induced cancer models.
J Mater Chem B
January 2025
Department of Chemistry, Indian Institute of Technology Indore, Indore 453552, India.
Mechanofluorochromic (MFC) materials are emerging as a versatile candidate for optoelectronic and biomedical applications. In the present work, we designed and synthesized four MFC materials, namely BT-PTZ-1, BT-PTZ-2, BT-PTZO-1, and BT-PTZO-2, using Suzuki cross-coupling reaction. These materials possess benzothiazole (BT) as an acceptor moiety and different donors, including phenothiazine (PTZ) and triphenylamine (TPA), with variations in their spacer units.
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