Wilms' tumours, neuroblastomas occurring in patients aged less than 1 year or localized neuroblastomas in older patients, malignant germ cells tumours, Hodgkin's disease, and malignant non Hodgkin lymphomas can be cured in more than 80% of the cases with treatment strategies adapted to risks factors in each tumour. The knowledge of low risk groups of patients allows the decrease of cumulative doses of alkylating agents and anthracyclines and limits the use of irradiation in order to reduce long term sequelae.
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Sci Rep
December 2024
Department of Medical and Surgical Sciences, Institute of Cardiology, University of Bologna, Policlinico S.Orsola-Malpighi, via Massarenti 9, Bologna, 40138, Italy.
Cardiac implantable electronic devices infections (CIEDI) are associated with poor survival despite the improvement in transvenous lead extraction (TLE). Aetiology and systemic involvement are driving factors of clinical outcomes. The aim of this study was to explore their contribute on overall mortality.
View Article and Find Full Text PDFFront Nutr
December 2024
Department of Urology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China.
Background: Bladder carcinoma is a type of urological tumor with high risks of recurrence and progression. The triglyceride-glucose (TyG) index has demonstrated significant promise as a prognostic marker for metabolic health in different types of cancer. Further research is needed to explore the relationships among non-muscle-invasive bladder cancer (NMIBC), the TyG index, and its prognostic importance.
View Article and Find Full Text PDFBMC Pregnancy Childbirth
December 2024
Department of Neurology, the First Affiliated Hospital of Wenzhou Medical University, Shangcai village, Ouhai District, Wenzhou, Zhejiang Province, P.R. China.
Background: We aim to develop a model to predict the probability of tonic-clonic seizures in women with epilepsy (WWE) at any point during pregnancy until six weeks postpartum.
Methods: We conducted a screening of patients diagnosed with epilepsy and who were pregnant, at a tertiary hospital in China, during the period of 1 January 2010 to 31 December 2020. We then followed up with these patients for at least one year postpartum.
BMC Musculoskelet Disord
December 2024
Department of Trauma and Microreconstructive Surgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, 830054, China.
Background: The purpose of this study was to report the clinical and psychological outcomes of using a locking compression plate (LCP) as a sequential external fixator following the distraction phase in the treatment of tibial bone defects caused by fracture-related infection (FRI).
Methods: We retrospectively analyzed the clinical records and consecutive X-ray images of patients with tibial bone defects who were treated with an LCP as a sequential external fixator following the distraction phase, between June 2017 and December 2022. The ASAMI criteria were applied to assess the bone and functional outcomes, and postoperative complications were evaluated by using the Paley classification.
BMC Musculoskelet Disord
December 2024
Department of Orthopedics, Peking University Third Hospital, No.49, North Garden Rd, HaiDian District, Beijing, 100191, China.
Background: Treating infectious bone defects combined with large soft-tissue lesions poses significant clinical challenges. Herein, we introduced a modified two-stage treatment approach involving the implantation of 3D-printed prostheses and flap repair to treat large segmental infectious tibial bone defects.
Method: We conducted a retrospective study of 13 patients treated at our center between April 2018 and March 2022 for tibial infections owing to posttraumatic infection and chronic osteomyelitis combined with soft tissue defects.
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