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A Composite Endpoint of Liver Surgery (CELS): Development and Validation of a Clinically Relevant Endpoint Requiring a Smaller Sample Size.
Ann Surg Oncol
January 2025
Department of Surgery, The Ohio State University Wexner Medical Center and James Comprehensive Cancer Center, Columbus, OH, USA.
Background: The feasibility of trials in liver surgery using a single-component clinical endpoint is low because single endpoints require large samples due to their low incidence. The current study sought to develop and validate a novel composite endpoint of liver surgery (CELS) to facilitate the generation of more feasible and robust high-level evidence in the field of liver surgery.
Methods: Patients who underwent curative-intent hepatectomy for hepatocellular carcinoma, intrahepatic cholangiocarcinoma, or colorectal liver metastasis were identified using a multi-institutional database.
Synergy of Pyridinic-N and Co Single Atom Sites for Enhanced Oxygen Redox Reactions in High-Performance Zinc-Air Batteries.
Small
January 2025
Department of Chemical and Biological Engineering, Monash University, Clayton, Victoria, 3800, Australia.
Cobalt single-atom catalysts (SACs) have the potential to act as bi-functional electrocatalysts for the oxygen-redox reactions in metal-air batteries. However, achieving both high performance and stability in these SACs has been challenging. Here, a novel and facile synthesis method is used to create cobalt-doped-nitrogen-carbon structures (Co-N-C) containing cobalt-SACs by carbonizing a modified ZIF-11.
View Article and Find Full Text PDFRolling the Dice with Light Competition: Introducing a True Random Number Generator Powered by Photo-Induced Polarity Current.
Adv Mater
January 2025
Department of Electronic Engineering, Hanyang University, 222 Wangsimni-ro, Seoul, Seoul, 04763, South Korea.
The pursuit of hardware-based security solutions has highlighted the true random number generator (TRNG). Various physical phenomena, from noise generation to quantum physics complexities, have been explored for random number generation. The arc discharge light-induced TRNG (ALTRNG) is introduced, featuring wavelength-dependent photocurrent generation and arc discharge irradiation.
View Article and Find Full Text PDFHabitat engineering by an apex predator generates spatial trophic dynamics across a temporal environmental stress gradient.
J Anim Ecol
January 2025
Department of Biological Sciences and Institute of Environment, Florida International University, Miami, Florida, USA.
Ecosystem engineering is a facilitative interaction that generates bottom-up extrinsic variability that may increase species coexistence, particularly along a stress/disturbance gradient. American alligators (Alligator mississippiensis) create and maintain 'alligator ponds' that serve as dry-season refuges for other animals. During seasonal water recession, these ponds present an opportunity to examine predictions of the stress-gradient (SGH) and intermediate disturbance hypotheses (IDH).
View Article and Find Full Text PDF3D Printed Spectroelectrochemical Platform for Redox-Based Bioelectronics.
Small Methods
January 2025
Fischell Department of Bioengineering, University of Maryland, College Park, MD, 20742, USA.
Redox provides unique opportunities for interconverting molecular/biological information into electronic signals. Here, the fabrication of a 3D-printed multiwell device that can be interfaced into existing laboratory instruments (e.g.
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