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Comparative evaluation of allograft particulate bone and cortical bone blocks combined with xenograft bone for labial bone defects in the aesthetic zone: a prospective cohort study.
BMC Oral Health
January 2025
State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Implant Dentistry, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, China.
Purpose: This study aimed to evaluate the osteogenic performance of allograft particulate bone and cortical bone blocks combined with xenograft under bovine pericardium membranes, for treating different degrees of labial bone defects in the aesthetic zone.
Materials And Methods: Twenty-four patients with bone defects were divided into two groups based on defect severity (Terheyden 1/4 and 2/4 groups). The Terheyden 1/4 group received granular bone grafts alone, while the Terheyden 2/4 group received cortical bone blocks combined with granular bone grafts.
Hydroxyapatite Chitosan Gradient Pore Scaffold Activates Oxidative Phosphorylation Pathway to Induce Bone Formation.
Front Biosci (Landmark Ed)
January 2025
Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Fujian Medical University, Fujian Provincial Key Laboratory of Stomatology, National Regional Medical Center, Binhai Campus of The First Affiliated Hospital, 350005 Fuzhou, Fujian, China.
Background: In this study, we prepared a porous gradient scaffold with hydroxyapatite microtubules (HAMT) and chitosan (CHS) and investigated osteogenesis induced by these scaffolds.
Methods: The arrangement of wax balls in the mold can control the size and distribution of the pores of the scaffold, and form an interconnected gradient pore structure. The scaffolds were systematically evaluated and for biocompatibility, biological activity, and regulatory mechanisms.
Improved Biomineralization Using Cellulose Acetate/Magnetic Nanoparticles Composite Membranes.
Polymers (Basel)
January 2025
Department of Dental Medicine and Nursing, Faculty of Medicine, Lucian Blaga University of Sibiu, 550169 Sibiu, Romania.
Following implantation, infections, inflammatory reactions, corrosion, mismatches in the elastic modulus, stress shielding and excessive wear are the most frequent reasons for orthopedic implant failure. Natural polymer-based coatings showed especially good results in achieving better cell attachment, growth and tissue-implant integration, and it was found that the inclusions of nanosized fillers in the coating structure improves biomineralization and consequently implant osseointegration, as the nanoparticles represent calcium phosphate nucleation centers and lead to the deposition of highly organized hydroxyapatite crystallites on the implant surface. In this study, magnetic nanoparticles synthesized by the co-precipitation method were used for the preparation of cellulose acetate composite coatings through the phase-inversion method.
View Article and Find Full Text PDFThe Assessment of Natural Biomineral Leonardite on Growth and Pigmentation of Goldfish, .
Life (Basel)
January 2025
Fisheries Faculty, Sinop University, 57000 Sinop, Turkey.
In this study, the impact of leonardite as a feed additive in goldfish diets was examined, focusing on its potential to positively influence feed and water parameters, which are critical for achieving sustainable ornamental fish farming. In this study, goldfish were fed diets containing four different levels of leonardite (0%, 2%, 6%, 10%). The experiment was conducted in 12 tanks with 3 replicates per treatment and lasted for 3 months.
View Article and Find Full Text PDFFabrication of Hard Tissue Constructs from Induced Pluripotent Stem Cells for Exploring Mechanisms of Hereditary Tooth/Skeletal Dysplasia.
Int J Mol Sci
January 2025
Division of Molecular & Regenerative Prosthodontics, Tohoku University Graduate School of Dentistry, Sendai 980-8575, Japan.
Tooth/skeletal dysplasia, such as hypophosphatasia (HPP), has been extensively studied. However, there are few definitive treatments for these diseases owing to the lack of an in vitro disease model. Cells differentiated from patient-derived induced pluripotent stem cells (iPSCs) demonstrate a pathological phenotype.
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