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Application of Anti-Motion Ultra-Fast Quantitative MRI in Neurological Disorder Imaging: Insights From Huntington's Disease.
J Magn Reson Imaging
January 2025
Department of Magnetic Resonance Imaging, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China.
Background: Conventional quantitative MRI (qMRI) scan is time-consuming and highly sensitive to movements, posing great challenges for quantitative images of individuals with involuntary movements, such as Huntington's disease (HD).
Purpose: To evaluate the potential of our developed ultra-fast qMRI technique, multiple overlapping-echo detachment (MOLED), in overcoming involuntary head motion and its capacity to quantitatively assess tissue changes in HD.
Study Type: Prospective.
A straightforward approach for 3D single-shot arterial spin labeling-based brain perfusion imaging: Preventing artifacts due to signal fluctuations.
Magn Reson Med
January 2025
F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, Maryland, USA.
Purpose: The present work aims to evaluate the performance of three-dimensional (3D) single-shot stack-of-spirals turbo FLASH (SOS-TFL) acquisition for pseudo-continuous arterial spin labeling (PCASL) and velocity-selective ASL (VSASL)-based cerebral blood flow (CBF) mapping, as well as VSASL-based cerebral blood volume (CBV) mapping.
Methods: Digital phantom simulations were conducted for both multishot echo planar imaging and spiral trajectories with intershot signal fluctuations. PCASL-derived CBF (PCASL-CBF), VSASL-derived CBF (VSASL-CBF), and CBV (VSASL-CBV) were all acquired using 3D multishot gradient and spin-echo and SOS-TFL acquisitions following background suppression.
Sulfur Lone Pairs Open Avenues for π* → n Orange-to-Red TADF and OLEDs.
J Am Chem Soc
January 2025
State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai 200438, China.
It is always important and fascinating to explore new organic emitters that exploit unconventional pathways to unveil their emission with unique properties, such as thermally activated delayed fluorescence (TADF). In this study, we report that the rarely explored sulfur lone pair (n) is a promising alternative, where the correlated π* → n emission can be used to attain strong TADF and thus practical OLEDs. The designed strategy incorporates several key concepts (Figure 1a), in which the persulfide aromatic spirocycle enhances spin-orbit coupling, thereby increasing the intersystem crossing rate.
View Article and Find Full Text PDFQuantum Analog of Landau-Lifshitz-Gilbert Dynamics.
Phys Rev Lett
December 2024
Uppsala University, Department of Physics and Astronomy, Box 516, SE-751 20 Uppsala, Sweden.
The Landau-Lifshitz-Gilbert (LLG) and Landau-Lifshitz (LL) equations play an essential role for describing the dynamics of magnetization in solids. While a quantum analog of the LL dynamics has been proposed in [Phys. Rev.
View Article and Find Full Text PDFUnified Variational Approach Description of Ground-State Phases of the Two-Dimensional Electron Gas.
Phys Rev Lett
December 2024
Flatiron Institute, Center for Computational Quantum Physics, New York, New York 10010, USA.
The two-dimensional electron gas (2DEG) is a fundamental model, which is drawing increasing interest because of recent advances in experimental and theoretical studies of 2D materials. Current understanding of the ground state of the 2DEG relies on quantum Monte Carlo calculations, based on variational comparisons of different Ansätze for different phases. We use a single variational ansatz, a general backflow-type wave function using a message-passing neural quantum state architecture, for a unified description across the entire density range.
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