Basing on the results of ultrasound dopplerography of the vertebral arteries of 337 patients with neurosensory hypoacusis (NSH), we identified 104 (30.9%) patients having vertebrobasilar hemodynamic disorders. We performed endaural phonoelectrophoresis of cavinton in modification, with application of the second electrode with vasoactive drugs on the region of cervical spine. This method of NSH treatment in patients with vertebral circulatory disorders showed clinical efficacy.

Download full-text PDF

Source

Publication Analysis

Top Keywords

neurosensory hypoacusis
8
circulatory disorders
8
[pharmacophysiotherapy combined
4
combined treatment
4
treatment neurosensory
4
hypoacusis presence
4
presence circulatory
4
disorders vertebral
4
vertebral arteries]
4
arteries] basing
4

Similar Publications

Lyme neuroborreliosis can present with isolated neurological manifestations, posing diagnostic challenges, especially in the absence of hallmark dermatological symptoms like erythema migrans. This case highlights a patient with isolated cervical radiculopathy due to Lyme neuroborreliosis, presenting without systemic features such as fever, arthralgia, or rash. The diagnosis was confirmed through serological testing, with positive findings on the Western blot.

View Article and Find Full Text PDF

Unveiling Secondary Mutations in Blended Phenotypes: Dual ERCC4 and OTOA Pathogenic Variants Through WES Analysis.

Int J Mol Sci

December 2024

Department of Biomedical and Biotechnological Sciences, Section of Clinical Biochemistry and Medical Genetics, University of Catania, via Santa Sofia, 95123 Catania, Italy.

This study describes two siblings from consanguineous parents who exhibit intellectual disability, microcephaly, photosensitivity, bilateral sensorineural hearing loss, numerous freckles, and other clinical features that suggest a potential disruption of the nucleotide excision repair (NER) pathway. Whole exome sequencing (WES) identified a novel homozygous missense variant in the gene, which was predicted to be pathogenic. However, a subsequent peculiar audiometric finding prompted further investigation, revealing a homozygous deletion in the gene linked to neurosensorial hearing loss.

View Article and Find Full Text PDF

Background: Sensorineural hearing loss (SNHL) is the most common sensory deficit worldwide. Current solutions for SNHL, including hearing aids, cochlear implants, and hearing assistive devices, do not provide consistent results and fail to address the underlying pathology of hair cell and ganglion cell damage. Stem cell therapy is a cornerstone in regenerative medicine.

View Article and Find Full Text PDF

Whole-exome sequencing reveals known and candidate genes for hearing impairment in Mali.

HGG Adv

January 2025

Division of Human Genetics, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa; McKusick-Nathans Institute, and Department of Genetic Medicine, Johns Hopkins University, School of Medicine, Baltimore, MD, USA. Electronic address:

Article Synopsis
  • *This study focused on the genetic causes of HI in the Malian population through whole exome sequencing, uncovering variants in multiple known HI genes and identifying a novel candidate gene, UBFD1.
  • *Results showed that 75% of the examined families had identifiable causes for HI, with many variants being newly identified and a case of digenic inheritance observed.
View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to explore how consistent use of hearing aids affects children's speech perception and vocabulary.
  • The analysis involved 29 children with hearing loss, looking at various factors like hearing aid usage, speech intelligibility, and vocabulary test scores.
  • Results indicated a positive link between vocabulary growth and increased hearing aid usage, highlighting the importance of regular device use in improving auditory skills.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!