Investigation of basic biochemical parameters of mixed saliva during sugar and urea tests including application of xidiphone has been carried out. Following parameters--pH, concentration of calcium, inorganic phosphate and fluoride--were measured. It was shown that xidiphone was an universal regulator of acid-base state, calcium-phosphorus an calcium-fluoride homeostasis in oral cavity.

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Investigation of basic biochemical parameters of mixed saliva during sugar and urea tests including application of xidiphone has been carried out. Following parameters--pH, concentration of calcium, inorganic phosphate and fluoride--were measured. It was shown that xidiphone was an universal regulator of acid-base state, calcium-phosphorus an calcium-fluoride homeostasis in oral cavity.

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It is well grounded for the application of a preparation from group bisphosphonates xydiphone is justified (reasonable). For treatment and preventive maintenance of a tooth stone for want of periodontal inflammation. Is shown on 30 patients with acute parodontitis and at 10--with gingivitis (in a stage of a peaking), that the application of xydiphone will neutralize an alkaline response having a place up to treatment, due to what it(he) exhibits antiseptic of a property.

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