Radiation necrosis of the brain after radiosurgery for vestibular schwannoma.

Am J Otolaryngol

Department of Otolaryngology, University of California, Irvine Medical Center, Orange, CA 92868, USA.

Published: January 2008

Objective: The objective of this study was to obtain a better understanding of radiation-induced brain necrosis after stereotactic radiation therapy for vestibular schwannomas.

Study Design: We conducted a retrospective case analysis.

Setting: The study took place at a tertiary referral center.

Patients: We report on the case of a patient treated with stereotactic radiation who developed radiation-induced necrosis of the ipsilateral temporal lobe.

Intervention: The various interventions in patients with radiation-induced necrosis include steroid treatment, decompression, and hyperbaric oxygen therapy; these are discussed briefly in this article. Owing to the limited symptoms in our patient, she was observed.

Main Outcome Measure: The outcome measure that we evaluated was radiation-induced necrosis of the brain after stereotactic radiation therapy for a vestibular schwannoma.

Results: Patients who undergo stereotactic radiation therapy for vestibular schwannomas are at risk for radiation-induced brain necrosis.

Conclusion: We support the development of a national database that would track the long-term complications of stereotactic radiation therapy to help patients make a more informed decision for the treatment of their vestibular schwannomas.

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Source
http://dx.doi.org/10.1016/j.amjoto.2006.09.008DOI Listing

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