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Fluorescence Polarization Immunoassay for Rapid, Sensitive Detection of the Herbicide 2,4-Dichlorophenoxyacetic Acid in Juice and Water Samples.
Biosensors (Basel)
January 2025
Faculty of Chemistry, M.V. Lomonosov Moscow State University, Leninsky Gory 1/3, 119991 Moscow, Russia.
2,4-Dichlorophenoxyacetic acid (2,4-D) is one of the popular herbicides that is widely used in agriculture and can be found in food and water. A rapid and sensitive fluorescence polarization immunoassay (FPIA) was proposed for the detection of 2,4-D in juice and water. New tracers, 2,4-D-buthylenediamin fluoresceinthiocarbamyl (2,4-D-BDF) and 2,4-D-glycine aminofluorescein (2,4-D-GAF), were obtained and characterized.
View Article and Find Full Text PDFReliability, measurement error, and validity of the Arabic version of the Patient-Specific Functional Scale in patients with upper extremity musculoskeletal disorders.
Disabil Rehabil
November 2024
Rehabilitation Sciences Department, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Article Synopsis
- - The study assessed the Arabic Patient-Specific Functional Scale (PSFS) for measuring functionality in individuals with upper extremity musculoskeletal disorders using various evaluation tools on 139 participants.
- - Results showed that the PSFS had excellent reliability (ICC = 0.82) and no major measurement issues, with specific correlations established between the PSFS and other scales like DASH and UEFI, affirming its construct validity.
- - The conclusion indicates that the Arabic PSFS is a reliable and valid tool for evaluating activity limitations in patients with upper extremity issues.
How Psychedelics Modulate Multiple Memory Mechanisms in Posttraumatic Stress Disorder.
Drugs
November 2024
Department of Psychiatry and Behavioral Sciences, Center for Psychedelic Research and Therapy, The University of Texas at Austin Dell Medical School, 1601 Trinity Street, Bldg. B, Stop Z0600, Austin, TX, 78712, USA.
Posttraumatic stress disorder (PTSD) is a psychiatric disorder with defining abnormalities in memory, and psychedelics may be promising candidates for the treatment of PTSD given their effects on multiple memory systems. Most PTSD and psychedelic research has investigated memory with fear conditioning and extinction. While fruitful, conditioning and extinction provide a limited model of the complexity of PTSD and phenomenology of psychedelics, thereby limiting the refinement of therapies.
View Article and Find Full Text PDFAffective Instability: Impact of Fluctuating Emotions on Regulation and Psychological Well-Being.
Behav Sci (Basel)
September 2024
Psychology Department, Grand Valley State University, Allendale, MI 49417, USA.
Previous research has focused on understanding the occurrence of intense and fluctuating emotions and the ability to manage these emotions and affective states. These phenomena have been, respectively, labeled as affective instability and emotion regulation and have been studied among individuals diagnosed with borderline personality disorder (BPD), attention-deficit/hyperactivity disorder (ADHD), bipolar disorder (BD), and post-traumatic stress disorder (PTSD). Previous findings suggest that affective instability may be associated with poorer psychological well-being.
View Article and Find Full Text PDFTracking neuroinflammatory biomarkers in Alzheimer's disease: a strategy for individualized therapeutic approaches?
J Neuroinflammation
July 2024
Oasi Research Institute-IRCCS, 94018, Troina, Italy.
Article Synopsis
- Recent drugs for Alzheimer's disease have not worked well and can cause serious problems.
- Scientists are looking at how inflammation in the brain might be linked to Alzheimer's and how it changes over time.
- New blood tests could help doctors understand Alzheimer's better and match treatments to individual patients based on their specific symptoms.
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