Objective: To explore the utility of Principal Factor Analysis (PFA) in chromatographic data for quality control.

Method: Chromatographic fingerprints of processed root pieces of Paeonia lactiflora were determined by HPLC, the PFA was used for data processing.

Result: The quantitative differences among different growing areas and different processing batches were found with the method.

Conclusion: The method could be used in quality control for monitoring between-batch products of traditional Chinese pharmaceutical process.

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