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HGF-DPSCs ameliorate asthma by regulating CCR1 Th2 cells responses in mice pulmonary mucosa.

Cytotherapy

February 2025

Health Management Institute, The Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, China. Electronic address:

Asthma, a prevalent allergic disease affecting approximately 300 million individuals globally, remains a significant public health challenge. Mesenchymal stromal cells (MSCs) and hepatocyte growth factor (HGF), both recognized for their immunomodulatory properties, hold therapeutic potential for asthma. However, their precise mechanisms remain underexplored.

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Introduction: This longitudinal study assessed the intermaxillary and intraarch relationships from mixed to permanent dentitions during a 4-year follow-up.

Methods: The sample comprised 352 children evaluated for crowding, midline maxillary diastema, anterior spacing, overjet, overbite, and sagittal and transverse relationships in mixed (T1) and permanent (T2) dentition. Data between different time points were compared using McNemar and Bowker symmetry tests, with a significance level of 5%.

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The physics of defect chemistry and the chemistry of defect physics.

Phys Chem Chem Phys

March 2025

Technical University of Darmstadt, Electronic Structure of Materials, Darmstadt, Germany.

Defect chemistry is the classical approach to evaluate point-defect concentrations in solids depending on the chemical activity of the ( - 1) of constituents by evaluating the mass action laws of a number of defect reactions conserving species, lattice sites, and charge. In an alternative approach, formation energies of individual defects can be calculated to determine the dependence on the Fermi level and on the chemical potentials of the reservoirs. This contribution provides the quantitative relationship between the two approaches, offering the opportunity to compare calculated defect formation energies with experimentally determined quantities.

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Validation of Diagnostic Utility of Washout CYFRA 21-1 in Lymph Node Metastasis of Thyroid Cancer.

Clin Cancer Res

March 2025

Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea, Seoul, Korea (South), Republic of.

Purpose: Traditional methods, fine-needle aspiration cytology (FNAC) and washout thyroglobulin (Tg), do not always provide sufficient accuracy for diagnosing lymph node (LN) metastasis in thyroid cancer. This study aimed to validate the diagnostic performance of washout cytokeratin fragment 21-1 (CYFRA 21-1) as a complementary biomarker for diagnosing metastatic LNs in thyroid cancer and to explore its relationship with molecular analysis and distant metastasis.

Patients And Methods: In this retrospective cohort study involving 230 LNs in 224 patients with PTC, FNAC, washout Tg, and CYFRA 21-1 levels were measured in suspicious LNs.

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Introduction: Various ventricular repolarization parameters are known to predict ventricular arrhythmias and mortality in various diseases. Although mortality in patients with heart failure with preserved ejection fraction (HFpEF) is similar to that in heart failure with reduced ejection fraction patients, studies on this subject are more limited. Therefore, it is important to evaluate the relationship between ventricular arrhythmias and mortality and ventricular repolarization parameters, especially the frontal plane QRS-T angle, in patients with HFpEF.

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