Clinicomorphological comparisons in 434 cases of destructive pancreatitis showed that macroscopic signs of destruction develop in the first 12 hours from the onset of the attack. The elaborated criteria make it possible to evaluate the main morphological components of destructive pancreatitis--pancreonecrosis proper, parapancreatitis, peritonitis, and "polyvisceritis" and to use therapeutic measures on an individual basis.

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