Imaging with spectroscopic micro-analysis using synchrotron radiation.

Anal Bioanal Chem

Sincrotrone Trieste, AREA Science Park, 34012, Trieste, Italy.

Published: October 2007

Recent developments of element-specific microscopy techniques using synchrotron radiation are opening new opportunities for the analytical investigation of various heterogeneous materials. This article provides a general description of the operational principles of different microscopes allowing chemical and structural imaging combined with micro-spot spectroscopic analysis. Several selected examples are used to illustrate the potential of the synchrotron-based methods in terms of imaging and chemical sensitivity for identification of spatial variations in the composition of morphologically complex and nano-structured inorganic and organic materials, including biological samples.

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http://dx.doi.org/10.1007/s00216-007-1532-4DOI Listing

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